Significant Enhancement of Circularly Polarized Luminescence Dissymmetry Factors in Quinoline Oligoamide Foldamers with Absolute Helicity.

When S- or R- oxazolylaniline enantiomers were attached to achiral quinoline oligoamide foldamers (QOFs), a single diastereomerically pure P- or M-handed foldamer was observed and exhibits negative or positive circularly polarized luminescence with the emission dissymmetry factors | glum| up to 0.038, which is significantly larger than that of QOF with incomplete chiral induction. More importantly, the CPL dissymmetry factors, together with the absorption dissymmetry factors, are enhanced with increases in the lengths of QOFs.