Mehdi Varmaghani1,2, Mina Dehghani2,3, Elham Heidari2, Farshad Sharifi4, Sahar Saeedi Moghaddam2,5, Farshad Farzadfar2,6. 1. Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran. 2. Non-Communicable Disease Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran. 3. Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran. 4. Elderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran. 5. Department of Biostatistics, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran. 6. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Abstract
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. AIMS: To synthesize data on the worldwide prevalence and severity of COPD by geographical region, age groups, and smoking status in a systematic review. METHODS: A systematic search was performed following Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines. International databases including PubMed, Scopus and Web of Science were searched for population- based studies published between January 2004 and May 2015 that reported the prevalence of COPD anywhere in the world. The prevalence of COPD was calculated based on World Health Organization (WHO) regions and sex and severity stages using metaprop. Meta-regression and subgroup analysis were applied to determine the sources of heterogeneity. RESULTS: Sixty papers were screened with a combined subject sample size of 127 598. The prevalence of post-bronchodilator COPD was 12.16% (10.91-13.40%). The pooled prevalence of COPD was 15.70% (13.80-18.59%) in men and 9.93% (8.73- 11.13%) in women. Among all WHO regions, the highest prevalence was recorded in the Region of the Americas (14.53%), and the lowest was recorded in the South-East Asia Region/Western Pacific Region (8.80%). Meta-regression model variables were: sample size, WHO region, study quality score, level of gathering data, publication year, and sampling methods that justified 29.82% of heterogeneity detected among COPD prevalence rates worldwide. CONCLUSIONS: Global prevalence of COPD among men is about 5% higher than among women. The most prevalent stage of COPD is stage 1.
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. AIMS: To synthesize data on the worldwide prevalence and severity of COPD by geographical region, age groups, and smoking status in a systematic review. METHODS: A systematic search was performed following Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines. International databases including PubMed, Scopus and Web of Science were searched for population- based studies published between January 2004 and May 2015 that reported the prevalence of COPD anywhere in the world. The prevalence of COPD was calculated based on World Health Organization (WHO) regions and sex and severity stages using metaprop. Meta-regression and subgroup analysis were applied to determine the sources of heterogeneity. RESULTS: Sixty papers were screened with a combined subject sample size of 127 598. The prevalence of post-bronchodilator COPD was 12.16% (10.91-13.40%). The pooled prevalence of COPD was 15.70% (13.80-18.59%) in men and 9.93% (8.73- 11.13%) in women. Among all WHO regions, the highest prevalence was recorded in the Region of the Americas (14.53%), and the lowest was recorded in the South-East Asia Region/Western Pacific Region (8.80%). Meta-regression model variables were: sample size, WHO region, study quality score, level of gathering data, publication year, and sampling methods that justified 29.82% of heterogeneity detected among COPD prevalence rates worldwide. CONCLUSIONS: Global prevalence of COPD among men is about 5% higher than among women. The most prevalent stage of COPD is stage 1.
Authors: Juan J Olortegui-Rodriguez; David R Soriano-Moreno; Alejandro Benites-Bullón; Pilar P Pelayo-Luis; Jorge Huaringa-Marcelo Journal: BMC Pulm Med Date: 2022-07-16 Impact factor: 3.320
Authors: Mehdi Varmaghani; Malihe Ghobadi; Farshad Sharifi; Payam Roshanfekr; Ali Sheidaei; Masoume Mansouri; Amin Adel; Mohammad Mohammadi; Mohammad Reza Masjedi Journal: Int J Prev Med Date: 2021-02-24
Authors: Yuanbin Chen; Lin Lin; Lei Wu; Yinji Xu; Johannah L Shergis; Anthony L Zhang; Zehuai Wen; Christopher Worsnop; Cliff Da Costa; Frank Thien; Charlie C Xue Journal: Int J Chron Obstruct Pulmon Dis Date: 2020-03-27
Authors: Su Won Lee; Yee Ran Lyu; So Jung Park; Jin Young Kwak; Won Kyung Yang; Seung Hyung Kim; Weechang Kang; Ji Woong Son; In Chul Jung; Yang Chun Park Journal: Medicine (Baltimore) Date: 2020-05 Impact factor: 1.817