Literature DB >> 30919086

B Cells Carrying Antigen Receptors Against Microbes as Tools for Vaccine Discovery and Design.

Deepika Bhullar1, David Nemazee2.   

Abstract

Can basic science improve the art of vaccinology? Here, we review efforts to understand immune responses with the aim to improve vaccine design and, eventually, to predict the efficacy of human vaccine candidates using the tools of transformed B cells and targeted transgenic mice carrying B cells with antigen receptors specific for microbes of interest.

Entities:  

Year:  2019        PMID： 30919086      PMCID： PMC6765437          DOI： 10.1007/82_2019_156

Source DB:  PubMed          Journal:  Curr Top Microbiol Immunol        ISSN： 0070-217X            Impact factor:   4.291


  131 in total

1.  T15-idiotype-negative B cells dominate the phosphocholine binding cells in the preimmune repertoire of T15i knockin mice.

Authors:  Lina Hu; Louis J Rezanka; Qing-Sheng Mi; Ana Lustig; Dennis D Taub; Dan L Longo; James J Kenny
Journal:  J Immunol       Date:  2002-02-01       Impact factor: 5.422

Review 2.  Critical assessment of human antibody generation in humanized mouse models.

Authors:  Julien Villaudy; Remko Schotte; Nicolas Legrand; Hergen Spits
Journal:  J Immunol Methods       Date:  2014-06-18       Impact factor: 2.303

3.  A highly conserved neutralizing epitope on group 2 influenza A viruses.

Authors:  Damian C Ekiert; Robert H E Friesen; Gira Bhabha; Ted Kwaks; Mandy Jongeneelen; Wenli Yu; Carla Ophorst; Freek Cox; Hans J W M Korse; Boerries Brandenburg; Ronald Vogels; Just P J Brakenhoff; Ronald Kompier; Martin H Koldijk; Lisette A H M Cornelissen; Leo L M Poon; Malik Peiris; Wouter Koudstaal; Ian A Wilson; Jaap Goudsmit
Journal:  Science       Date:  2011-07-07       Impact factor: 47.728

Review 4.  Polysaccharide vaccines as probes of antibody repertoires in man.

Authors:  A H Lucas; D C Reason
Journal:  Immunol Rev       Date:  1999-10       Impact factor: 12.988

5.  Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls.

Authors:  Laurent Verkoczy; Yao Chen; Hilary Bouton-Verville; Jinsong Zhang; Marilyn Diaz; Jennifer Hutchinson; Ying-Bin Ouyang; S Munir Alam; T Matt Holl; Kwan-Ki Hwang; Garnett Kelsoe; Barton F Haynes
Journal:  J Immunol       Date:  2011-09-09       Impact factor: 5.422

6.  Anti-HIV B Cell lines as candidate vaccine biosensors.

Authors:  Takayuki Ota; Colleen Doyle-Cooper; Anthony B Cooper; Michael Huber; Emilia Falkowska; Katherine J Doores; Lars Hangartner; Khoa Le; Devin Sok; Joseph Jardine; Jeffrey Lifson; Xueling Wu; John R Mascola; Pascal Poignard; James M Binley; Bimal K Chakrabarti; William R Schief; Richard T Wyatt; Dennis R Burton; David Nemazee
Journal:  J Immunol       Date:  2012-10-12       Impact factor: 5.422

7.  Antiviral immune responses in gene-targeted mice expressing the immunoglobulin heavy chain of virus-neutralizing antibodies.

Authors:  Lars Hangartner; Beatrice M Senn; Birgit Ledermann; Ulrich Kalinke; Peter Seiler; Etienne Bucher; Raphaël M Zellweger; Katja Fink; Bernhard Odermatt; Kurt Bürki; Rolf M Zinkernagel; Hans Hengartner
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-20       Impact factor: 11.205

8.  Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs.

Authors:  Sam Hoot; Andrew T McGuire; Kristen W Cohen; Roland K Strong; Lars Hangartner; Florian Klein; Ron Diskin; Johannes F Scheid; D Noah Sather; Dennis R Burton; Leonidas Stamatatos
Journal:  PLoS Pathog       Date:  2013-01-03       Impact factor: 6.823

9.  Autoreactivity and exceptional CDR plasticity (but not unusual polyspecificity) hinder elicitation of the anti-HIV antibody 4E10.

Authors:  Kathryn A K Finton; Kevin Larimore; H Benjamin Larman; Della Friend; Colin Correnti; Peter B Rupert; Stephen J Elledge; Philip D Greenberg; Roland K Strong
Journal:  PLoS Pathog       Date:  2013-09-26       Impact factor: 6.823

10.  Positive selection of anti-thy-1 autoreactive B-1 cells and natural serum autoantibody production independent from bone marrow B cell development.

Authors:  Kyoko Hayakawa; Masanao Asano; Susan A Shinton; Ming Gui; Li-Jun Wen; Joni Dashoff; Richard R Hardy
Journal:  J Exp Med       Date:  2003-01-06       Impact factor: 14.307
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.