Literature DB >> 30918915

Aerobic Exercise Improves Quality of Life and CD4 Cell Counts in HIV Seropositives in Nigeria.

Stanley M Maduagwu1, Weszani Gashau2, Adamu Balami3, Amina Kaidal3, A Y Oyeyemi4, Ballah Akawu Danue2, Chuka Ifenyi Umeonwuka4, O A Akanbi1.   

Abstract

BACKGROUND: Studies that examine the effectiveness of exercise on quality of life and CD4 cells of HIV population are not easily available in developing countries.
PURPOSE: This study was therefore aimed at investigating the effect of 12 weeks aerobic exercise on quality of life and CD4 cells of HIV seropositives in Nigeria.
METHODS: Using convenient sampling, 91 volunteer and willing HIV infected persons were enrolled in the study. Based on inclusion criteria, 82 were eligible for the study, and randomly assigned to control and experimental groups. After determining the baseline values of the variables, the experimental group participated in moderate intensity aerobic exercise for 12 weeks. Weekly lectures were organized for the control group. Attrition rate of 22% was recorded at the end the study, leaving 32 participants in each group. The variables were re-assessed at the end of the Descriptive statistic summarized the socio-demographic characteristics of the participants. Paired Student t-test and Student t-test for two independent samples analyzed the significant difference in mean values of the variables.
RESULTS: Mean ages in years of the control and experimental groups were39.38 10.03 and 40.84 ± 10.05 respectively, and that of the 64 participants was 39.57±10.13. There was significant improvement (p < 0.05) in the variables between pre- and post-tests in the experimental group. There was insignificant change (p > 0.05) in the four domains of quality of life of the participants, and significant reduction (p < 0.05) in the other four domains of this variable between pre- and post-tests in the control group, in CD4 cell counts, significant improvement was recorded. The variables at the end of the study showed significant difference (p < 0.05) between both groups.
CONCLUSION: Quality of life and CD4 cells of HIV seropositives in the experimental group improved significantly after 12 weeks moderate intensity aerobic exercise.

Entities:  

Keywords:  Aerobic exercise; Attrition rate; CD4 cell counts; Convenient sampling; HIV seropositives; Quality of life

Year:  2017        PMID: 30918915      PMCID: PMC6433410          DOI: 10.15406/jhvrv.2017.05.00151

Source DB:  PubMed          Journal:  J Hum Virol Retrovirol        ISSN: 2373-6453


  26 in total

1.  Management of anxiety and depression in HIV-infected patients.

Authors:  R P Cabaj
Journal:  J Int Assoc Physicians AIDS Care       Date:  1996-06

2.  Sleep disturbance in early HIV infection.

Authors:  D F Darko; M M Mitler; J L White
Journal:  Focus       Date:  1995-10

3.  Association between exercise and HIV disease progression in a cohort of homosexual men.

Authors:  T Mustafa; F S Sy; C A Macera; S J Thompson; K L Jackson; A Selassie; L L Dean
Journal:  Ann Epidemiol       Date:  1999-02       Impact factor: 3.797

4.  Lipodystrophy in 685 HIV-1-treated patients: influence of antiretroviral treatment and immunovirological response.

Authors:  F Boufassa; A Dulioust; A S Lascaux; L Meyer; F Boué; J F Delfraissy; A Sobel; C Goujard
Journal:  HIV Clin Trials       Date:  2001 Jul-Aug

5.  The effects of massage therapy alone and in combination with other complementary therapies on immune system measures and quality of life in human immunodeficiency virus.

Authors:  T J Birk; A McGrady; R D MacArthur; S Khuder
Journal:  J Altern Complement Med       Date:  2000-10       Impact factor: 2.579

6.  Moderate and high intensity exercise training in HIV-1 seropositive individuals: a randomized trial.

Authors:  L Terry; E Sprinz; J P Ribeiro
Journal:  Int J Sports Med       Date:  1999-02       Impact factor: 3.118

7.  Correlates of sleep quality in persons with HIV disease.

Authors:  K M Nokes; J Kendrew
Journal:  J Assoc Nurses AIDS Care       Date:  2001 Jan-Feb       Impact factor: 1.354

8.  Cardiopulmonary and CD4 cell changes in response to exercise training in early symptomatic HIV infection.

Authors:  F M Perna; A LaPerriere; N Klimas; G Ironson; A Perry; J Pavone; A Goldstein; P Majors; D Makemson; C Talutto; N Schneiderman; M A Fletcher; O G Meijer; L Koppes
Journal:  Med Sci Sports Exerc       Date:  1999-07       Impact factor: 5.411

9.  Psychological symptoms among persons 50 years of age and older living with HIV disease.

Authors:  T G Heckman; B D Heckman; A Kochman; K J Sikkema; J Suhr; K Goodkin
Journal:  Aging Ment Health       Date:  2002-05       Impact factor: 3.658

Review 10.  Depression in patients with HIV infection.

Authors:  S R Penzak; Y S Reddy; S R Grimsley
Journal:  Am J Health Syst Pharm       Date:  2000-02-15       Impact factor: 2.637

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