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Literature DB >> 30915953

Case Report: A Case of Type 1 Leprosy Reaction and Dapsone Hypersensitivity Syndrome Complicating the Clinical Course of Multibacillary Leprosy.

Jeffrey Craig^1,2, Cara MacRae³, Rochelle G Melvin⁴, Andrea K Boggild^5,1,6.

Abstract

Type 1 reactions, characterized by increasing lesion erythema, pain, and nerve damage, commonly complicate leprosy. Dapsone hypersensitivity syndrome (DHS) is a potentially fatal reaction occurring 6-8 weeks into dapsone therapy. We present a case of intercurrent Type 1 reaction and DHS in a multibacillary leprosy patient recently started on multidrug treatment.

Entities: Chemical Disease Species

Mesh：

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Year: 2019 PMID： 30915953 PMCID： PMC6493923 DOI： 10.4269/ajtmh.18-0953

Source DB: PubMed Journal: Am J Trop Med Hyg ISSN： 0002-9637 Impact factor: 2.345

18 in total

Review 1. Reactive metabolites and adverse drug reactions: clinical considerations.

Authors: Sandra R Knowles; Lori E Shapiro; Neil H Shear
Journal: Clin Rev Allergy Immunol Date: 2003-06 Impact factor: 8.667

2. Dapsone hypersensitivity syndrome.

Authors: R Prussick; N H Shear
Journal: J Am Acad Dermatol Date: 1996-08 Impact factor: 11.527

3. Diagnosis of sulfonamide hypersensitivity reactions by in-vitro "rechallenge" with hydroxylamine metabolites.

Authors: M J Rieder; J Uetrecht; N H Shear; M Cannon; M Miller; S P Spielberg
Journal: Ann Intern Med Date: 1989-02-15 Impact factor: 25.391

Review 4. Hypersensitivity reactions to rifampin. Pathogenetic mechanisms, clinical manifestations, management strategies, and review of the anaphylactic-like reactions.

Authors: E Martínez; J Collazos; J Mayo
Journal: Medicine (Baltimore) Date: 1999-11 Impact factor: 1.889

5. Severe dapsone hypersensitivity syndrome.

Authors: O Sener; L Doganci; M Safali; B Besirbellioglu; F Bulucu; A Pahsa
Journal: J Investig Allergol Clin Immunol Date: 2006 Impact factor: 4.333

Review 6. 10. Drug allergy.

Authors: Rebecca S Gruchalla
Journal: J Allergy Clin Immunol Date: 2003-02 Impact factor: 10.793

Case Report: A Case of Type 1 Leprosy Reaction and Dapsone Hypersensitivity Syndrome Complicating the Clinical Course of Multibacillary Leprosy.

Review 1. Reactive metabolites and adverse drug reactions: clinical considerations.

2. Dapsone hypersensitivity syndrome.

3. Diagnosis of sulfonamide hypersensitivity reactions by in-vitro "rechallenge" with hydroxylamine metabolites.

Review 4. Hypersensitivity reactions to rifampin. Pathogenetic mechanisms, clinical manifestations, management strategies, and review of the anaphylactic-like reactions.

5. Severe dapsone hypersensitivity syndrome.

Review 6. 10. Drug allergy.

7. Dapsone hypersensitivity syndrome among leprosy patients in China.

Review 8. Leprosy: a primer for Canadian physicians.

9. Dapsone hypersensitivity syndrome: A rare life threatening complication of dapsone therapy.

10. A case of serum sickness-like reaction and anaphylaxis - induced simultaneously by rifampin.

Review 1. A review of nutrition in neuropathic pain of leprosy.