Literature DB >> 3091541

Thyroid stimulating and gonadotrophic hormones in pituitary adenomas without clinical or serological abnormality.

E Hitchcock, C S Morris.   

Abstract

Forty-three chromophobe adenomas have been examined immunocytochemically for their hormonal content. Twelve cases with full pre-operative normal serum hormonal levels were found to have many positive cells within the tumour for thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). The specificity of the immunoreactive product within the tissue was checked by immunoabsorption. It is suggested that a non-secreted biologically inactive glycoprotein hormone is produced by tumour clones.

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Year:  1986        PMID: 3091541     DOI: 10.1007/bf01675209

Source DB:  PubMed          Journal:  Histochem J        ISSN: 0018-2214


  14 in total

1.  Multihormonal pituitary adenomas.

Authors:  P U Heitz
Journal:  Horm Res       Date:  1979

2.  Secretion of alpha subunit of glycoprotein hormones by pituitary adenomas.

Authors:  I A Kourides; B D Weintraub; S W Rosen; E C Ridgway; B Kliman; F Maloof
Journal:  J Clin Endocrinol Metab       Date:  1976-07       Impact factor: 5.958

3.  Abnormal secretion of glycoprotein alpha-subunit and follicle-stimulating hormone (FSH) beta-subunit in men with pituitary adenomas and FSH hypersecretion.

Authors:  P J Snyder; J Johnson; R Muzyka
Journal:  J Clin Endocrinol Metab       Date:  1980-09       Impact factor: 5.958

4.  Pituitary adenomas: clinicopathological and immunohistochemical study.

Authors:  A J Martinez; A Lee; J Moossy; J C Maroon
Journal:  Ann Neurol       Date:  1980-01       Impact factor: 10.422

5.  Human mixed somatotrophic and lactotrophic pituitary adenomas.

Authors:  B Corenblum; A M Sirek; E Horvath; K Kovacs; C Ezrin
Journal:  J Clin Endocrinol Metab       Date:  1976-05       Impact factor: 5.958

6.  Pituitary hyperthyroidism. Case report and review of the literature.

Authors:  G Tolis; C Bird; G Bertrand; J M McKenzie; C Ezrin
Journal:  Am J Med       Date:  1978-01       Impact factor: 4.965

7.  Pituitary adenomas associated with elevated blood follicle-stimulating hormone levels: a histologic, immunocytologic, and electron microscopic study of two cases.

Authors:  K Kovacs; E Horvath; G R Van Loon; N B Rewcastle; C Ezrin; A A Rosenbloom
Journal:  Fertil Steril       Date:  1978-06       Impact factor: 7.329

8.  Pituitary adenomas: immunohistology and ultrastructural analysis of 118 tumors.

Authors:  M M Esiri; C B Adams; C Burke; R Underdown
Journal:  Acta Neuropathol       Date:  1983       Impact factor: 17.088

9.  Clinical and histopathological characteristics of gonadotropin-producing pituitary adenomas.

Authors:  M Miura; Y Matsukado; T Kodama; Y Mihara
Journal:  J Neurosurg       Date:  1985-03       Impact factor: 5.115

10.  In vitro secretion of follicle-stimulating hormone by pituitary chromophobe adenomas.

Authors:  J Takeuchi; H Handa; K Suda; T Aso
Journal:  Surg Neurol       Date:  1980-10
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