Literature DB >> 30912980

Small molecules as central nervous system therapeutics: old challenges, new directions, and a philosophic divide.

William A Banks1,2, Nigel H Greig3.   

Abstract

Keywords:  biologics; blood–brain barrier; brain; central nervous system; clinical trials; pharmacokinetics; small molecules; therapeutics; tight junction proteins; variance

Year:  2019        PMID： 30912980     DOI： 10.4155/fmc-2018-0436

Source DB:  PubMed          Journal:  Future Med Chem        ISSN： 1756-8919            Impact factor:   3.808


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  8 in total

1.  Basic physiology of the blood-brain barrier in health and disease: a brief overview.

Authors:  Mehmet Kaya; Bulent Ahishali
Journal:  Tissue Barriers       Date:  2020-11-15

2.  Drug Delivery Strategies to Overcome the Blood-Brain Barrier (BBB).

Authors:  Hans Christian Cederberg Helms; Mie Kristensen; Lasse Saaby; Gert Fricker; Birger Brodin
Journal:  Handb Exp Pharmacol       Date:  2022

Review 3.  Repurposing Immunomodulatory Imide Drugs (IMiDs) in Neuropsychiatric and Neurodegenerative Disorders.

Authors:  Yoo Jin Jung; David Tweedie; Michael T Scerba; Dong Seok Kim; Maria Francesca Palmas; Augusta Pisanu; Anna R Carta; Nigel H Greig
Journal:  Front Neurosci       Date:  2021-03-29       Impact factor: 4.677

Review 4.  Advances and Challenges in Intranasal Delivery of Antipsychotic Agents Targeting the Central Nervous System.

Authors:  Manisha Pandey; Neha Jain; Jovita Kanoujia; Zahid Hussain; Bapi Gorain
Journal:  Front Pharmacol       Date:  2022-03-24       Impact factor: 5.810

Review 5.  Applications of Phyto-Nanotechnology for the Treatment of Neurodegenerative Disorders.

Authors:  Tanima Bhattacharya; Giselle Amanda Borges E Soares; Hitesh Chopra; Md Mominur Rahman; Ziaul Hasan; Shasank S Swain; Simona Cavalu
Journal:  Materials (Basel)       Date:  2022-01-21       Impact factor: 3.623

6.  Repurposing Pomalidomide as a Neuroprotective Drug: Efficacy in an Alpha-Synuclein-Based Model of Parkinson's Disease.

Authors:  Maria Francesca Palmas; Anna Ena; Chiara Burgaletto; Maria Antonietta Casu; Giuseppina Cantarella; Ezio Carboni; Michela Etzi; Alfonso De Simone; Giuliana Fusco; Maria Cristina Cardia; Francesco Lai; Luca Picci; David Tweedie; Michael T Scerba; Valentina Coroneo; Renato Bernardini; Nigel H Greig; Augusta Pisanu; Anna R Carta
Journal:  Neurotherapeutics       Date:  2022-01-24       Impact factor: 6.088

7.  Microglia-targeting nanotherapeutics for neurodegenerative diseases.

Authors:  Nanxia Zhao; Nicola L Francis; Hannah R Calvelli; Prabhas V Moghe
Journal:  APL Bioeng       Date:  2020-09-08

Review 8.  Neuroinflammation as a Factor of Neurodegenerative Disease: Thalidomide Analogs as Treatments.

Authors:  Yoo Jin Jung; David Tweedie; Michael T Scerba; Nigel H Greig
Journal:  Front Cell Dev Biol       Date:  2019-12-04
  8 in total

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