Prashant N Mohite1, Diana García Sáez2, Andrew J Butler3, Christopher J E Watson3, Andre Simon2. 1. Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield Hospital, Harefield, United Kingdom. Electronic address: p.mohite@rbht.nhs.uk. 2. Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield Hospital, Harefield, United Kingdom. 3. Department of Surgery, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.
Abstract
PURPOSE: We wanted to evaluate if direct procurement of the heart is possible in combination with normothermic regional perfusion of abdominal organs in donors after circulatory death. DESCRIPTION: A donation after circulatory death pathway was used for a 41-year-old woman after an irreversible brain injury. After meeting criteria for the organ donation, the heart was retrieved and re-animated on ex situ perfusion system, and abdominal organs were perfused with normothermic regional perfusion. EVALUATION: All the donated organs and their recipients had excellent short-term outcome. CONCLUSIONS: We demonstrated a successful combination of direct procurement of the heart and normothermic regional perfusion of the abdominal organs.
PURPOSE: We wanted to evaluate if direct procurement of the heart is possible in combination with normothermic regional perfusion of abdominal organs in donors after circulatory death. DESCRIPTION: A donation after circulatory death pathway was used for a 41-year-old woman after an irreversible brain injury. After meeting criteria for the organ donation, the heart was retrieved and re-animated on ex situ perfusion system, and abdominal organs were perfused with normothermic regional perfusion. EVALUATION: All the donated organs and their recipients had excellent short-term outcome. CONCLUSIONS: We demonstrated a successful combination of direct procurement of the heart and normothermic regional perfusion of the abdominal organs.