Literature DB >> 3090839

The effect of sympathetic denervation with 6-hydroxydopamine on the ventral prostate of the rat.

A Vaalasti, A M Alho, H Tainio, A Hervonen.   

Abstract

The effect of chemical sympathectomy with 6-hydroxydopamine (6-OHDA) on the ventral prostate of the rat was studied. A dose of 50 mg/kg i.v., which was repeated after 1 week, was effective enough to produce total disappearance of sympathetic nerves. Reappearance of nerve fibres was evident 2 weeks after treatment. Dilation of prostatic alveoli was noted 1 week after denervation. It is concluded that the absence of normal sympathetic innervation prevents the emptying of the rat prostate.

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Year:  1986        PMID: 3090839     DOI: 10.1016/S0065-1281(86)80099-X

Source DB:  PubMed          Journal:  Acta Histochem        ISSN: 0065-1281            Impact factor:   2.479


  2 in total

1.  Expression of nerve growth factor in the prostate of male rats in response to chronic stress and sympathetic denervation.

Authors:  Shengliang Huang; Xuebei Zhang; Liuyu Xu; Qing Li; Qingli Zhao
Journal:  Exp Ther Med       Date:  2014-07-21       Impact factor: 2.447

2.  Influence of the neural microenvironment on prostate cancer.

Authors:  Christian Coarfa; Diego Florentin; NagiReddy Putluri; Yi Ding; Jason Au; Dandan He; Ahmed Ragheb; Anna Frolov; George Michailidis; MinJae Lee; Dov Kadmon; Brian Miles; Christopher Smith; Michael Ittmann; David Rowley; Arun Sreekumar; Chad J Creighton; Gustavo Ayala
Journal:  Prostate       Date:  2017-11-13       Impact factor: 4.104

  2 in total

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