Literature DB >> 30906718

Outcome of Endoscopic Cerebrospinal Fluid Rhinorrhoea Repair: An Institutional Study.

Sudhir Majhi1, Akriti Sharma1.   

Abstract

Cerebrospinal fluid Rhinorrhoea is caused by an abnormal open communication between the subarachnoid space and the nasal cavity. The most common anatomic sites of such abnormal communication are found in the anterior skull base, namely, ethmoid roof, olfactory groove, roof of the sphenoid sinus and the posterior wall of the frontal sinus. It can be classified into traumatic or spontaneous. Spontaneous leaks are associated with highest recurrence rates following surgical repair. The repair of CSF Rhinorrhoea has rapidly evolved over the past 30 years. Prior to the advent of the endoscopic approach, craniotomy was used for repairs which carried a variable success rate and morbidity. The purpose of our study was to ascertain the outcome after Transnasal Endoscopic Repair of spontaneous CSF leaks. This was a prospective study conducted at the Department of ENT at Safdarjung Hospital, New Delhi between January 2015 and June 2016. The study comprised of eleven patients who presented with the complaint of watery nasal discharge and were diagnosed to have spontaneous CSF Rhinorrhoea. Proper clinical examination, nasal endoscopy and biochemical and cytological analysis of nasal secretions of the patient was done. High Resolution Computed Tomography and MRI scans of the nose and paranasal sinuses were done to identify precise location of CSF leak and the size of fistula. CT cisternography was done wherever required. Fistula was repaired via Transnasal endoscopic approach in a multi layered underlay fashion. Out of all eleven patients with spontaneous CSF leaks, most common site of leak was from left cribriform area. Four patients (36.36%) were found to have meningoencephalocele. No associated intracranial lesion was found and all patients did not have any benign intracranial hypertension. Our success rate of endoscopic repair on first attempt was 100% with recurrence in 1 patient after 4 months of repair. Endoscopic repair of CSF rhinorrhoea is safe and effective, with a very low complication rate. It has almost completely replaced the older open techniques. Accurate localization of leak site followed by multilayered closure of dural defect appear to be essential for successful endoscopic repair.

Entities:  

Keywords:  CSF leaks; Cerebrospinal fluid rhinorrhoea; Cribriform plate; Meningoencephalocele; Transnasal endoscopic repair

Year:  2018        PMID: 30906718      PMCID: PMC6401007          DOI: 10.1007/s12070-018-1485-2

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  17 in total

1.  Comparison of beta2-transferrin and beta-trace protein for detection of cerebrospinal fluid in nasal and ear fluids.

Authors:  Claudia Schnabel; Ercole Di Martino; Joachim M Gilsbach; Dieter Riediger; Axel M Gressner; Dagmar Kunz
Journal:  Clin Chem       Date:  2004-03       Impact factor: 8.327

Review 2.  Management of unexpected cerebrospinal fluid leak during endoscopic sinus surgery.

Authors:  Michael P Platt; Steven M Parnes
Journal:  Curr Opin Otolaryngol Head Neck Surg       Date:  2009-02       Impact factor: 2.064

3.  Transnasal endoscopic treatment of cerebrospinal fluid leak: 17 years' experience.

Authors:  L Presutti; F Mattioli; D Villari; D Marchioni; M Alicandri-Ciufelli
Journal:  Acta Otorhinolaryngol Ital       Date:  2009-08       Impact factor: 2.124

4.  CSF rhinorrhoea: the place of endoscopic sinus surgery.

Authors:  A H Marshall; N S Jones; I J Robertson
Journal:  Br J Neurosurg       Date:  2001-02       Impact factor: 1.596

5.  Endoscopic cerebrospinal fluid rhinorrhea repair: is a lumbar drain necessary?

Authors:  R R Casiano; D Jassir
Journal:  Otolaryngol Head Neck Surg       Date:  1999-12       Impact factor: 3.497

6.  Transnasal endoscopic repair of cerebrospinal fluid rhinorrhea: a meta-analysis.

Authors:  H M Hegazy; R L Carrau; C H Snyderman; A Kassam; J Zweig
Journal:  Laryngoscope       Date:  2000-07       Impact factor: 3.325

7.  Primary spontaneous cerebrospinal fluid rhinorrhea and obesity.

Authors:  L Badia; S Loughran; V Lund
Journal:  Am J Rhinol       Date:  2001 Mar-Apr

8.  Endoscopic endonasal approaches for repair of cerebrospinal fluid leaks: nine-year experience.

Authors:  Davide Locatelli; Federico Rampa; Ilaria Acchiardi; Maurizio Bignami; Francesca De Bernardi; Paolo Castelnuovo
Journal:  Neurosurgery       Date:  2006-04       Impact factor: 4.654

9.  Skull base cerebrospinal fluid fistulas: a comprehensive diagnostic algorithm.

Authors:  Jeffrey S Zapalac; Bradley F Marple; Nathan D Schwade
Journal:  Otolaryngol Head Neck Surg       Date:  2002-06       Impact factor: 3.497

10.  Endoscopic closure of CSF rhinorrhea: 193 cases over 21 years.

Authors:  Caroline A Banks; James N Palmer; Alexander G Chiu; Bert W O'Malley; Bradford A Woodworth; David W Kennedy
Journal:  Otolaryngol Head Neck Surg       Date:  2009-02-28       Impact factor: 3.497

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  1 in total

1.  Diagnostic Value of Non-Contrast CT in Cerebrospinal Fluid Leakage After Endoscopic Transnasal Surgery for Sellar and Suprasellar Tumors.

Authors:  Wei Gao; Xiaoyu Wang; Yuanjian Fang; Yuan Hong; Wei Yan; Sheng Zhang; Chenguang Li
Journal:  Front Oncol       Date:  2022-01-20       Impact factor: 6.244

  1 in total

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