Rosa Monno1, Vittoriana De Laurentiis2, Paolo Trerotoli3, Anna Maria Roselli4, Enzo Ierardi5, Piero Portincasa6. 1. Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, P. Giulio Cesare 70124 Bari, Italy. Electronic address: rosa.monno@uniba.it. 2. Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, P. Giulio Cesare 70124 Bari, Italy. Electronic address: vittoriana.delaurentiis@gmail.com. 3. Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, P. Giulio Cesare 70124 Bari, Italy. Electronic address: paolo.trerotoli@uniba.it. 4. Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, P. Giulio Cesare 70124 Bari, Italy. Electronic address: annamros1@gmail.com. 5. Department of Emergency and Organ Transplantation University of Bari Aldo Moro, P. Giulio Cesare 70124 Bari, Italy. Electronic address: ierardi.enzo@gmail.com. 6. Clinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, P. Giulio Cesare 70124 Bari, Italy. Electronic address: piero.portincasa@uniba.it.
Abstract
INTRODUCTION: Few studies have investigated factors possibly related to the source of Helicobacter pylori infection in humans. MATERIALS AND METHODS: This was a retrospective study including a population of 201 H.pylori positive patients and 259 H. pylori negative subjects observed at a tertiary referral center in Apulia. The H. pylori status was assessed by urea breath test. Data on socio-demographic characteristics and the consumption of different foods and beverages in the last year were collected by a questionnaire. RESULTS: No significant relationship was found between H. pylori infection and gender or age, type of employment, working in direct contact with the public, residence, level of education or exposure to pets. No association between H.pylori status and the consumption of fish, fruits, legumes, honey, spices, meats, milk and milk products including some typical product of our area was found. The same was true for the consumption of several kind of beverage including green tea and wine. Cigarette smoking and living in the same house with H.pylori positive relatives were significantly associated with H. pylori positivity. The intake of uncooked seafood (mussels and other molluscs) as well as some uncooked vegetables such as tomatos,pepper,and chicory,municipal water and the number of cups of coffee consumed per week correlated significantly with H. pylori status. The consumption of raw vegetables purchased from street vendors and the consumption of meals outside home were also associated with H.pylori infection. CONCLUSIONS: Foods may represent an important route in the transmission of H. pylori among humans.
INTRODUCTION: Few studies have investigated factors possibly related to the source of Helicobacter pyloriinfection in humans. MATERIALS AND METHODS: This was a retrospective study including a population of 201 H.pylori positive patients and 259 H. pylori negative subjects observed at a tertiary referral center in Apulia. The H. pylori status was assessed by urea breath test. Data on socio-demographic characteristics and the consumption of different foods and beverages in the last year were collected by a questionnaire. RESULTS: No significant relationship was found between H. pyloriinfection and gender or age, type of employment, working in direct contact with the public, residence, level of education or exposure to pets. No association between H.pylori status and the consumption of fish, fruits, legumes, honey, spices, meats, milk and milk products including some typical product of our area was found. The same was true for the consumption of several kind of beverage including green tea and wine. Cigarette smoking and living in the same house with H.pylori positive relatives were significantly associated with H. pylori positivity. The intake of uncooked seafood (mussels and other molluscs) as well as some uncooked vegetables such as tomatos,pepper,and chicory,municipal water and the number of cups of coffee consumed per week correlated significantly with H. pylori status. The consumption of raw vegetables purchased from street vendors and the consumption of meals outside home were also associated with H.pylori infection. CONCLUSIONS: Foods may represent an important route in the transmission of H. pylori among humans.
Authors: Amir Hossein Miri; Mojtaba Kamankesh; Antoni Llopis-Lorente; Chenguang Liu; Matthias G Wacker; Ismaeil Haririan; Hamid Asadzadeh Aghdaei; Michael R Hamblin; Abbas Yadegar; Mazda Rad-Malekshahi; Mohammad Reza Zali Journal: Front Pharmacol Date: 2022-06-27 Impact factor: 5.988
Authors: Xiujuan Xia; Linfang Zhang; Hao Wu; Feng Chen; Xuanyou Liu; Huifang Xu; Yuqi Cui; Qiang Zhu; Meifang Wang; Hong Hao; De-Pei Li; William P Fay; Luis A Martinez-Lemus; Michael A Hill; Canxia Xu; Zhenguo Liu Journal: Front Cardiovasc Med Date: 2022-03-31