Literature DB >> 30904883

Unusual presentation of extramedullary haematopoiesis in a young boy.

Pramod Darole1, Uma Sundar1, Nilesh Kuchekar1, Ajay Karre1.   

Abstract

Acute transverse myelopathy in a young person may be due to infection, postinfective or inflammatory demyelination, or vascular causes. Rarely, a completely reversible cause of acute transverse myelopathy may be seen, as described here in our case of transverse myelopathy due to extramedullary haematopoiesis (EMH). An 18-year-old man who had a history of a lone blood transfusion at age of 7 years presented with paraplegia. MRI showed multiple epidural space masses of EMH compressing the spinal cord. He was detected to have thalassaemia intermedia and was treated with blood transfusions, steroids and radiotherapy to the involved paraspinal areas. He recovered fully over 15 days and remained symptom free at 6 months. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  haematology (incl blood transfusion); spinal cord

Mesh:

Year:  2019        PMID: 30904883      PMCID: PMC6453391          DOI: 10.1136/bcr-2018-227199

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  21 in total

1.  Hypertransfusion: a successful method of treatment in thalassemia intermedia patients with spinal cord compression secondary to extramedullary hematopoiesis.

Authors:  Aref Chehal; Elie Aoun; Salam Koussa; Hadi Skoury; Suzanne Koussa; Ali Taher
Journal:  Spine (Phila Pa 1976)       Date:  2003-07-01       Impact factor: 3.468

2.  [Compression of the spinal cord due to proliferation of bone marrow in epidural space in a splenectomized person with Cooley's disease].

Authors:  I GATTO; V TERRANA; L BIONDI
Journal:  Haematologica       Date:  1954       Impact factor: 9.941

Review 3.  Paraspinal extramedullary hematopoiesis in patients with thalassemia intermedia.

Authors:  Rachid Haidar; Hani Mhaidli; Ali T Taher
Journal:  Eur Spine J       Date:  2010-03-05       Impact factor: 3.134

4.  Spinal cord compression: a rareness in pregnant thalassemic woman.

Authors:  V Phupong; B Uerpairojkij; S Limpongsanurak
Journal:  J Obstet Gynaecol Res       Date:  2000-04       Impact factor: 1.730

5.  The role of radiation therapy in the management of spinal cord compression due to extramedullary haematopoiesis in thalassaemia.

Authors:  S Singhal; S Sharma; S Dixit; S De; S Chander; G K Rath; V S Mehta
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-04       Impact factor: 10.154

6.  Extramedullary hemopoiesis with multiple tumor-simulating mediastinal masses in hemoglobin E-thalassemia disease.

Authors:  J L Da Costa; Y S Loh; E Hanam
Journal:  Chest       Date:  1974-02       Impact factor: 9.410

Review 7.  [Extramedullary hematopoiesis of thoracic and vertebral intraductal localization. Apropos of a case. Review of the literature].

Authors:  C Evrard; D Pichereau; S Alsweis; B Martel; F Galateau; J P Houtteville; A Benazza; M Leporrier
Journal:  Ann Chir       Date:  1994

Review 8.  Spinal extradural hematopoiesis in adolescents with thalassemia. Report of two cases and a review of the literature.

Authors:  A Amirjamshidi; K Abbassioun; S E Ketabchi
Journal:  Childs Nerv Syst       Date:  1991-08       Impact factor: 1.475

9.  Incidence and clinical study of ectopic erythropoiesis in adult patients with thalassemia intermedia.

Authors:  F Dore; P Cianciulli; S Rovasio; L Oggiano; S Bonfigli; M Murineddu; S Pardini; G Simonetti; G Gualdi; G Papa
Journal:  Ann Ital Med Int       Date:  1992 Jul-Sep

10.  Spinal Cord Compression Secondary to Extramedullary Hematopoiesis: Case Report and Review of the Literature.

Authors:  Arthur Wang; Nathan Carberry; Elena Solli; John Gillick; Humayun Islam; Virany Hillard
Journal:  Case Rep Oncol       Date:  2016-05-31
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