Adam Omari1, Christian Medom Madsen2, Jes Bruun Lauritzen3,4, Henrik Løvendahl Jørgensen4,5, Fie Juhl Vojdeman6. 1. Faculty of Health and Medical Sciences, Copenhagen University, Copenhagen, Denmark. 2. Department of Clinical Biochemistry, Herlev & Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark. 3. Department of Orthopedic Surgery, Bispebjerg Frederiksberg Hospital, Copenhagen, Denmark. 4. Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. 5. Department of Clinical Biochemistry, Hvidovre Hospital, Hvidovre, Denmark. 6. Department of Clinical Biochemistry, Bispebjerg Frederiksberg Hospital, Copenhagen, Denmark. fie.juhl.vojdeman@regionh.dk.
Abstract
PURPOSE: This nationwide study assessed associations between comorbidity and mortality after hip fracture in young and middle-aged patients. METHODS: Data on 19,682 patients aged 18 to 65 years were extracted from Danish registries out of 154,047 patients who experienced a hip fracture between 1996 and 2012. Mortality and comorbidity were assessed using information on vital status, hospital admissions, and prescriptions. RESULTS: Of the 19,682 patients 17,722 (90.0%) were middle-aged (40-65 years) and 1960 (10.0%) were young (18-39 years). The 30-day mortality rates were 3.2% (n = 570) and 1.6% (n = 32), respectively. Indicators of multi-trauma (hazard ratio (HR), 3.5 95% confidence interval (CI) [1.6-7.8], n = 2056) and having diabetes (HR, 4.4 [1.2-11.3], n = 59) and heart disease (HR, 4.4[1.3-14.8], n = 57) increased 30-day mortality in the young patients, while having cancer (HR, 5.0 [4.2-5.9], n = 1958) increased 30-day mortality in the middle-aged patients. CONCLUSION: Heart disease and diabetes were associated with high mortality in the young patients while having cancer was associated with high mortality in the middle-aged patients.
PURPOSE: This nationwide study assessed associations between comorbidity and mortality after hip fracture in young and middle-aged patients. METHODS: Data on 19,682 patients aged 18 to 65 years were extracted from Danish registries out of 154,047 patients who experienced a hip fracture between 1996 and 2012. Mortality and comorbidity were assessed using information on vital status, hospital admissions, and prescriptions. RESULTS: Of the 19,682 patients 17,722 (90.0%) were middle-aged (40-65 years) and 1960 (10.0%) were young (18-39 years). The 30-day mortality rates were 3.2% (n = 570) and 1.6% (n = 32), respectively. Indicators of multi-trauma (hazard ratio (HR), 3.5 95% confidence interval (CI) [1.6-7.8], n = 2056) and having diabetes (HR, 4.4 [1.2-11.3], n = 59) and heart disease (HR, 4.4[1.3-14.8], n = 57) increased 30-day mortality in the young patients, while having cancer (HR, 5.0 [4.2-5.9], n = 1958) increased 30-day mortality in the middle-aged patients. CONCLUSION:Heart disease and diabetes were associated with high mortality in the young patients while having cancer was associated with high mortality in the middle-aged patients.
Entities:
Keywords:
Age; Comorbidity; Diabetes; Heart disease; Hip fracture
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