Literature DB >> 30903222

Faster union rate and better clinical outcomes using autologous bone graft after medial opening wedge high tibial osteotomy.

Woon-Hwa Jung1, Ryohei Takeuchi2, Dong-Hyun Kim3, Ramvilas Nag3.   

Abstract

PURPOSE: To compare the radiological bone union rate after medial opening wedge high tibial osteotomy (MOW-HTO) and stabilization using a TomoFix™ plate (Synthes, Oberdorf, Switzerland) in three patient groups.
METHODS: Retrospective analysis of 137 knees that underwent MOW-HTO between January 2014 and January 2017 was using a TomoFix™ plate. Osteotomy gaps were filled with β-tricalcium phosphate (β-TCP) (group A), left unfilled (group B), and subject to autologous bone graft and β-TCP (group C). Radiological bone union using simple radiography was determined by a modified version of the Brosset et al. osteotomy filling index. Clinical outcomes were evaluated using the International Knee Documentation Committee (IKDC) and Lysholm score. Statistical analyses using the Chi-square and ANOVA tests were performed between the groups.
RESULTS: The mean time for radiological bone union was 8.3 ± 3.1 months in group A, 7.2 ± 3.2 in group B and 3.4 ± 1.5 in group C (p = 0.001). There was statistically significant faster bone union in Group C. If the opening distance was more than 10 mm, group A united in 8.6 ± 3.6 months, group B in 8.8 ± 3.4, and group C in 3.5 ± 1.7 (p = 0.001). IKDC and Lysholm knee scores improved significantly (p = 0.004 for IKDC and 0.001 for Lysholm knee scores) in group C when compared to groups A and B at sixth month follow-up. At final follow-up, there was no difference in IKDC and Lysholm knee scores. Less delayed union occurred in group C.
CONCLUSIONS: MOW-HTO with autologous bone graft and β-TCP had the fastest radiological bone union and best clinical scores at 6 month follow-up. LEVEL OF EVIDENCE: Retrospective comparative study, Level III.

Entities:  

Keywords:  Autologous bone grafting; Bone union; Knee; Open wedge high tibial osteotomy; Osteoarthritis; Osteotomy gap

Year:  2019        PMID: 30903222     DOI: 10.1007/s00167-019-05463-w

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  23 in total

1.  TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia--early results in 92 cases.

Authors:  Alex E Staubli; Carlo De Simoni; Reto Babst; Philipp Lobenhoffer
Journal:  Injury       Date:  2003-11       Impact factor: 2.586

Review 2.  Preoperative planning for high tibial osteotomy. The effect of lateral tibiofemoral separation and tibiofemoral length.

Authors:  T W Dugdale; F R Noyes; D Styer
Journal:  Clin Orthop Relat Res       Date:  1992-01       Impact factor: 4.176

3.  Satisfactory functional and radiological outcomes can be expected in young patients under 45 years old after open wedge high tibial osteotomy in a long-term follow-up.

Authors:  Michael E Hantes; Prodromos Natsaridis; Antonios A Koutalos; Yohei Ono; Nikolaos Doxariotis; Konstantinos N Malizos
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-11-30       Impact factor: 4.342

4.  Opening-wedge high tibial osteotomy without bone graft.

Authors:  Maher A El-Assal; Yaser E Khalifa; Mohamed M Abdel-Hamid; Hatem G Said; Hatem M A Bakr
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-03-27       Impact factor: 4.342

Review 5.  Bone grafts and bone substitutes for opening-wedge osteotomies of the knee: a systematic review.

Authors:  Nicholas J Lash; Julian A Feller; Lachlan M Batty; Jason Wasiak; Anneka K Richmond
Journal:  Arthroscopy       Date:  2015-01-14       Impact factor: 4.772

6.  Autologous Osteophyte Grafting for Open-Wedge High Tibial Osteotomy.

Authors:  Takenori Akiyama; Ken Okazaki; Taro Mawatari; Satoshi Ikemura; Shunsuke Nakamura
Journal:  Arthrosc Tech       Date:  2016-09-05

7.  Comparative study of medial opening-wedge high tibial osteotomy using 2 different implants.

Authors:  Woon-Hwa Jung; Chung-Woo Chun; Ji-Hoon Lee; Jae-Hun Ha; Ji-Hyae Kim; Jae-Heon Jeong
Journal:  Arthroscopy       Date:  2013-04-26       Impact factor: 4.772

Review 8.  The role of bone void fillers in medial opening wedge high tibial osteotomy: a systematic review.

Authors:  Omer Slevin; Olufemi R Ayeni; Stefan Hinterwimmer; Thomas Tischer; Matthias J Feucht; Michael T Hirschmann
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-08-24       Impact factor: 4.342

9.  Primary stability of different plate positions and the role of bone substitute in open wedge high tibial osteotomy.

Authors:  Ryohei Takeuchi; Jung Woon-Hwa; Hiroyuki Ishikawa; Yuichiro Yamaguchi; Katsunari Osawa; Yasushi Akamatsu; Koichi Kuroda
Journal:  Knee       Date:  2017-10-13       Impact factor: 2.199

10.  Posterior cortical breakage leads to posterior tibial slope change in lateral hinge fracture following opening wedge high tibial osteotomy.

Authors:  Sung-Sahn Lee; Kyung-Wook Nha; Dae-Hee Lee
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2018-05-21       Impact factor: 4.342

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  5 in total

1.  A Novel Quantitative Evaluation of Bone Formation After Opening Wedge High Tibial Osteotomy Using Tomosynthesis.

Authors:  Kyota Ishibashi; Eiji Sasaki; Edward Wijaya; Shohei Yamauchi; Shizuka Sasaki; Yuka Kimura; Yuji Yamamoto; Takashi Shimbo; Katsuto Tamai; Yasuyuki Ishibashi
Journal:  J Digit Imaging       Date:  2022-04-13       Impact factor: 4.903

2.  Better functional results of opening wedge HTO for varus knees with medial osteoarthritis than opening wedge LFO for valgus knees with lateral osteoarthritis.

Authors:  Arne Ekeland; Tor Kjetil Nerhus; Sigbjørn Dimmen; Stig Heir
Journal:  Bone Jt Open       Date:  2020-11-02

3.  The Development of a Magnesium-Releasing and Long-Term Mechanically Stable Calcium Phosphate Bone Cement Possessing Osteogenic and Immunomodulation Effects for Promoting Bone Fracture Regeneration.

Authors:  Jun Wu; Feihong Liu; Zejin Wang; Yuan Liu; Xiaoli Zhao; Christian Fang; Frankie Leung; Kelvin W K Yeung; Tak Man Wong
Journal:  Front Bioeng Biotechnol       Date:  2022-01-11

4.  Effectiveness of bone substitute materials in opening wedge high tibial osteotomy: a systematic review and meta-analysis.

Authors:  Tao Bei; Liping Yang; Qiulin Huang; Jiaheng Wu; Junting Liu
Journal:  Ann Med       Date:  2022-12       Impact factor: 4.709

5.  New insight into the current study of high tibial osteotomy: A bibliometric analysis.

Authors:  Cong Wei; Wenqing Xie; Wenchao Zhang; Ning Tang; Yang Su; Buchan Jiang; Lucas H Walschot; Haijun Xu; Yusheng Li; Tianlong Huang
Journal:  Medicine (Baltimore)       Date:  2022-09-16       Impact factor: 1.817

  5 in total

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