Efi Parpa1, Eleni Tsilika1, Antonis Galanos1, Maria Nikoloudi1, Kyriaki Mystakidou2. 1. Pain Relief and Palliative Care Unit, Department of Radiology, Areteion Hospital, School of Medicine, National & Kapodistrian University of Athens, 27 Korinthias St., 115 26, Athens, Greece. 2. Pain Relief and Palliative Care Unit, Department of Radiology, Areteion Hospital, School of Medicine, National & Kapodistrian University of Athens, 27 Korinthias St., 115 26, Athens, Greece. mistakidou@yahoo.com.
Abstract
PURPOSE: Previous findings have shown that depression in advanced stages of cancer is associated with hopelessness and frequently with wishes for hastened death. The current study tries to investigate the relationship between hopelessness and desire for hastened death and if depression may be a moderator and/or mediator role in patients with advanced cancer. METHOD: The participants were 102 patients with advanced cancer which they completed the Beck Hopelessness Scale (BHS), the Greek Schedule of Attitudes towards Hastened Death (G-SAHD), and the Greek Beck Depression Inventory (BDI). RESULTS: Depression was highly correlated with hopelessness and desire for hastened death. Mediation analyses revealed that hopelessness influenced desire for hastened death as well as indirectly by its effect on depression. Similarly, depression was found as moderator in the relationship between hopelessness with desire for hastened death. CONCLUSIONS: Hopelessness and desire for hastened death in patients with advanced cancer should be diagnosed and treated by taking into consideration the optimum care of depression as a priority in palliative care.
PURPOSE: Previous findings have shown that depression in advanced stages of cancer is associated with hopelessness and frequently with wishes for hastened death. The current study tries to investigate the relationship between hopelessness and desire for hastened death and if depression may be a moderator and/or mediator role in patients with advanced cancer. METHOD: The participants were 102 patients with advanced cancer which they completed the Beck Hopelessness Scale (BHS), the Greek Schedule of Attitudes towards Hastened Death (G-SAHD), and the Greek Beck Depression Inventory (BDI). RESULTS:Depression was highly correlated with hopelessness and desire for hastened death. Mediation analyses revealed that hopelessness influenced desire for hastened death as well as indirectly by its effect on depression. Similarly, depression was found as moderator in the relationship between hopelessness with desire for hastened death. CONCLUSIONS: Hopelessness and desire for hastened death in patients with advanced cancer should be diagnosed and treated by taking into consideration the optimum care of depression as a priority in palliative care.
Entities:
Keywords:
Advanced cancer; Depression; Hastened death; Hopelessness; Mediator; Moderator
Authors: Jane Walker; Christian Holm Hansen; Paul Martin; Stefan Symeonides; Ravi Ramessur; Gordon Murray; Michael Sharpe Journal: Lancet Psychiatry Date: 2014-08-28 Impact factor: 27.083
Authors: Stephen Ross; Gabrielle Agin-Liebes; Sharon Lo; Richard J Zeifman; Leila Ghazal; Julia Benville; Silvia Franco Corso; Christian Bjerre Real; Jeffrey Guss; Anthony Bossis; Sarah E Mennenga Journal: ACS Pharmacol Transl Sci Date: 2021-03-18