| Literature DB >> 30899627 |
Phillip Knouse1, Christie Hancock1, Suzanne Iwaz2, Pamela Kaiser1.
Abstract
Metastatic carcinomatosis cirrhosis is a pattern of metastasis in which malignancy infiltrates the liver and provokes hepatic fibrosis. It is an especially rare complication of several malignancies, including breast cancer. We report a case of a 61-year-old woman with lobular carcinoma of the breast who presented with confusion and rising serum tumor markers without evidence of disease recurrence on imaging. She subsequently developed clinical evidence of hepatic dysfunction and a liver biopsy revealed diffuse infiltration of the liver by breast carcinoma with surrounding fibrous tissue deposition, consistent with metastatic carcinomatosis cirrhosis. This case highlights a rare and clinically significant pattern of metastasis and is the first to describe lobular carcinoma of the breast causing metastatic carcinomatosis cirrhosis.Entities:
Keywords: breast cancer; hepatic cirrhosis; hepatic tumor; liver cirrhosis; liver failure; liver metastases; metastatic disease
Year: 2019 PMID: 30899627 PMCID: PMC6420322 DOI: 10.7759/cureus.3876
Source DB: PubMed Journal: Cureus ISSN: 2168-8184