Literature DB >> 30899627

Metastatic Carcinomatosis Cirrhosis: A Rare Pattern of Metastasis.

Phillip Knouse1, Christie Hancock1, Suzanne Iwaz2, Pamela Kaiser1.   

Abstract

Metastatic carcinomatosis cirrhosis is a pattern of metastasis in which malignancy infiltrates the liver and provokes hepatic fibrosis. It is an especially rare complication of several malignancies, including breast cancer. We report a case of a 61-year-old woman with lobular carcinoma of the breast who presented with confusion and rising serum tumor markers without evidence of disease recurrence on imaging. She subsequently developed clinical evidence of hepatic dysfunction and a liver biopsy revealed diffuse infiltration of the liver by breast carcinoma with surrounding fibrous tissue deposition, consistent with metastatic carcinomatosis cirrhosis. This case highlights a rare and clinically significant pattern of metastasis and is the first to describe lobular carcinoma of the breast causing metastatic carcinomatosis cirrhosis.

Entities:  

Keywords:  breast cancer; hepatic cirrhosis; hepatic tumor; liver cirrhosis; liver failure; liver metastases; metastatic disease

Year:  2019        PMID: 30899627      PMCID: PMC6420322          DOI: 10.7759/cureus.3876

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  2 in total

1.  MetastaSite: Predicting metastasis to different sites using deep learning with gene expression data.

Authors:  Somayah Albaradei; Abdurhman Albaradei; Asim Alsaedi; Mahmut Uludag; Maha A Thafar; Takashi Gojobori; Magbubah Essack; Xin Gao
Journal:  Front Mol Biosci       Date:  2022-07-22

2.  Radiographically Occult Carcinomatous Spread of Breast Cancer to the Liver: A Challenging Case.

Authors:  Trish Millard; Akriti Gupta; Christiana Brenin; Paul Marshall; Patrick Dillon
Journal:  Case Rep Oncol Med       Date:  2019-12-06
  2 in total

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