Literature DB >> 30898918

Dampening oncogenic RAS signaling.

Trever G Bivona1.   

Abstract

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Year:  2019        PMID： 30898918     DOI： 10.1126/science.aav6703

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


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  9 in total

1.  BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition.

Authors:  Marco H Hofmann; Michael Gmachl; Juergen Ramharter; Fabio Savarese; Daniel Gerlach; Joseph R Marszalek; Michael P Sanderson; Dirk Kessler; Francesca Trapani; Heribert Arnhof; Klaus Rumpel; Dana-Adriana Botesteanu; Peter Ettmayer; Thomas Gerstberger; Christiane Kofink; Tobias Wunberg; Andreas Zoephel; Szu-Chin Fu; Jessica L Teh; Jark Böttcher; Nikolai Pototschnig; Franziska Schachinger; Katharina Schipany; Simone Lieb; Christopher P Vellano; Jonathan C O'Connell; Rachel L Mendes; Jurgen Moll; Mark Petronczki; Timothy P Heffernan; Mark Pearson; Darryl B McConnell; Norbert Kraut
Journal:  Cancer Discov       Date:  2020-08-19       Impact factor: 39.397

2.  Synthesis and structural characterization of a monocarboxylic inhibitor for GRB2 SH2 domain.

Authors:  Tao Xiao; Luxin Sun; Min Zhang; Zilu Li; Eric B Haura; Ernst Schonbrunn; Haitao Ji
Journal:  Bioorg Med Chem Lett       Date:  2021-09-07       Impact factor: 2.823

3.  Development of a cell-free split-luciferase biochemical assay as a tool for screening for inhibitors of challenging protein-protein interaction targets.

Authors:  Rachel Cooley; Neesha Kara; Ning Sze Hui; Jonathan Tart; Chloë Roustan; Roger George; David C Hancock; Brock F Binkowski; Keith V Wood; Mohamed Ismail; Julian Downward
Journal:  Wellcome Open Res       Date:  2020-02-06

Review 4.  Targeting Oncogenic BRAF: Past, Present, and Future.

Authors:  Aubhishek Zaman; Wei Wu; Trever G Bivona
Journal:  Cancers (Basel)       Date:  2019-08-16       Impact factor: 6.639

5.  Quantitative Trait Module-Based Genetic Analysis of Alzheimer's Disease.

Authors:  Shaoxun Yuan; Haitao Li; Jianming Xie; Xiao Sun
Journal:  Int J Mol Sci       Date:  2019-11-25       Impact factor: 5.923

6.  The RAS-PI3K-AKT-NF-κB pathway transcriptionally regulates the expression of BCL2 family and IAP family genes and inhibits apoptosis in fibrous epulis.

Authors:  Yangyang Jiang; Bing Fang; Bin Xu; Liang Chen
Journal:  J Clin Lab Anal       Date:  2019-11-19       Impact factor: 2.352

7.  Oncogenic RAS instructs morphological transformation of human epithelia via differential tissue mechanics.

Authors:  Agata Nyga; Jose J Muñoz; Suze Dercksen; Giulia Fornabaio; Marina Uroz; Xavier Trepat; Buzz Baum; Helen K Matthews; Vito Conte
Journal:  Sci Adv       Date:  2021-10-13       Impact factor: 14.136

Review 8.  BRAF Mutations in Colorectal Liver Metastases: Prognostic Implications and Potential Therapeutic Strategies.

Authors:  Pei-Pei Wang; Chen Lin; Jane Wang; Georgios Antonios Margonis; Bin Wu
Journal:  Cancers (Basel)       Date:  2022-08-23       Impact factor: 6.575

9.  Analysis of RAS gene mutations in cytogenetically normal de novo acute myeloid leukemia patients reveals some novel alterations.

Authors:  Afia Muhammad Akram; Asma Chaudhary; Humera Kausar; Fayez Althobaiti; Afshan Syed Abbas; Zawar Hussain; Naz Fatima; Erum Zafar; Wajiha Asif; Umair Afzal; Zoufishan Yousaf; Amjad Zafar; Steve M Harakeh; Samina Qamer
Journal:  Saudi J Biol Sci       Date:  2021-05-06       Impact factor: 4.219
  9 in total

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