Literature DB >> 30898580

A hyaluronan/methylcellulose-based hydrogel for local cell and biomolecule delivery to the central nervous system.

Margaret T Ho1, Carter J Teal1, Molly S Shoichet2.   

Abstract

Regenerative medicine strategies rely on exogenous cell transplantation and/or endogenous cell stimulation. Biomaterials can help to increase the regenerative potential of cells and biomolecules by controlling transplanted cell fate and provide a local, sustained release of biomolecules. In this review, we describe the use of a hyaluronan/methylcellulose (HAMC)-based hydrogel as a delivery vehicle to the brain, spinal cord, and retina to promote cellular survival and tissue repair. We discuss various controlled release strategies to prolong the delivery of factors for neuroprotection. The versatility of this hydrogel for a diversity of applications highlights its potential to enhance cell- and biomolecule-based treatment strategies.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Blindness; Cell delivery; Drug delivery; Hydrogel; Spinal cord injury; Stroke

Mesh：

Substances：

Year:  2019        PMID： 30898580     DOI： 10.1016/j.brainresbull.2019.03.005

Source DB:  PubMed          Journal:  Brain Res Bull        ISSN： 0361-9230            Impact factor:   4.077


  16 in total

1.  Functional resveratrol-biodegradable manganese doped silica nanoparticles for the spinal cord injury treatment.

Authors:  Xue Jiang; Xiaoyao Liu; Qi Yu; Wenwen Shen; Xifan Mei; He Tian; Chao Wu
Journal:  Mater Today Bio       Date:  2021-12-04

Review 2.  Engineering Tissues of the Central Nervous System: Interfacing Conductive Biomaterials with Neural Stem/Progenitor Cells.

Authors:  Rebecca D Bierman-Duquette; Gevick Safarians; Joyce Huang; Bushra Rajput; Jessica Y Chen; Ze Zhong Wang; Stephanie K Seidlits
Journal:  Adv Healthc Mater       Date:  2021-12-16       Impact factor: 9.933

Review 3.  Biomaterial-Based Schwann Cell Transplantation and Schwann Cell-Derived Biomaterials for Nerve Regeneration.

Authors:  Zilong Rao; Zudong Lin; Panpan Song; Daping Quan; Ying Bai
Journal:  Front Cell Neurosci       Date:  2022-06-28       Impact factor: 6.147

Review 4.  A roadmap for promoting endogenous in situ tissue restoration using inductive bioscaffolds after acute brain injury.

Authors:  Michel Modo; Stephen F Badylak
Journal:  Brain Res Bull       Date:  2019-05-22       Impact factor: 3.715

5.  Electric Field Application In Vivo Regulates Neural Precursor Cell Behavior in the Adult Mammalian Forebrain.

Authors:  Elana Sefton; Stephanie N Iwasa; Taylor Morrison; Hani E Naguib; Milos R Popovic; Cindi M Morshead
Journal:  eNeuro       Date:  2020-08-24

Review 6.  Applying hiPSCs and Biomaterials Towards an Understanding and Treatment of Traumatic Brain Injury.

Authors:  María Lacalle-Aurioles; Camille Cassel de Camps; Cornelia E Zorca; Lenore K Beitel; Thomas M Durcan
Journal:  Front Cell Neurosci       Date:  2020-11-12       Impact factor: 5.505

Review 7.  Marine Biocompounds for Neuroprotection-A Review.

Authors:  Adrian Florian Bălașa; Cristina Chircov; Alexandru Mihai Grumezescu
Journal:  Mar Drugs       Date:  2020-05-31       Impact factor: 5.118

Review 8.  Neurorestoration Approach by Biomaterials in Ischemic Stroke.

Authors:  Noelia Esteban-Garcia; Cristina Nombela; Javier Garrosa; Fernando J Rascón-Ramirez; Juan Antonio Barcia; Leyre Sánchez-Sánchez-Rojas
Journal:  Front Neurosci       Date:  2020-05-12       Impact factor: 5.152

Review 9.  Bioscaffold-Induced Brain Tissue Regeneration.

Authors:  Michel Modo
Journal:  Front Neurosci       Date:  2019-11-07       Impact factor: 5.152

10.  Invertebrate Retinal Progenitors as Regenerative Models in a Microfluidic System.

Authors:  Caroline D Pena; Stephanie Zhang; Robert Majeska; Tadmiri Venkatesh; Maribel Vazquez
Journal:  Cells       Date:  2019-10-22       Impact factor: 6.600
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.