| Literature DB >> 30896698 |
Han Xue1, Fei Ding, Jiao Zhang, Yuanyuan Guo, Xihui Gao, Jing Feng, Xinyuan Zhu, Chuan Zhang.
Abstract
DNA tetrahedra are employed as building blocks to construct a novel DNA-based nanogel for intracellular siRNA delivery. With a compact architecture that embeds functional siRNA inside, the self-assembled nanogel can efficiently enter cells and knock down the target gene expression, making them potential noncationic vectors for functional nucleic acid delivery.Mesh：
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Year: 2019 PMID： 30896698 DOI： 10.1039/c9cc00175a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222