Literature DB >> 30893095

A Pilot Study of Oxytocin in Low-Income Women With a Low Birth-Weight Infant: Is Oxytocin Related to Posttraumatic Stress?

Lindsey Garfield1, Diane Holditch-Davis, C Sue Carter, Barbara L McFarlin, Julia S Seng, Carmen Giurgescu, Rosemary White-Traut.   

Abstract

BACKGROUND: Negative outcomes related to prematurity may lead to maternal distress. Mothers of premature/low birth-weight infants report increased posttraumatic stress (50%) and depressive symptoms (63%) compared with mothers of full-term infants. Low-income, minority mothers with greater posttraumatic stress and depression have an increased risk for premature/low birth-weight delivery compared with their white counterparts. Variations in the neuropeptide oxytocin are implicated in lactation, perinatal depression, and maternal behavior.
PURPOSE: To examine the associations among posttraumatic stress, depressive symptoms, and oxytocin in a pilot sample of minority mothers with premature/low birth-weight infants in the neonatal intensive care unit (NICU).
METHODS: This study employed a descriptive, correlational pilot design of 8 minority, low-income mothers with premature/low birth-weight infants. Participants answered questionnaires pertaining to posttraumatic stress, depression, lactation, and demographics and oxytocin was measured. This is a substudy that added oxytocin values.
RESULTS: Four participants had elevated depressive symptoms and 5 supplied their own milk. Women who provided their own milk had lower depressive (t = 3.03, P = .023) and posttraumatic stress (t = 3.39, P = .015) symptoms compared with women not supplying their own milk. Women with elevated posttraumatic stress had higher levels of depressive symptoms (r(8) = 0.8, P = .006) and lower levels of oxytocin (r(8) = 0.77, P = .026). IMPLICATIONS FOR PRACTICE: These results are congruent with previous literature on providing human milk and maternal mental health. In addition, we found a possible relationship between postpartum posttraumatic stress and oxytocin in minority women with premature/low birth-weight infants. NICU nurses should encourage lactation and assess mothers for posttraumatic stress and depressive symptoms. IMPLICATIONS FOR RESEARCH: Research is needed to identify the biologic milieu associated with posttraumatic stress and depression in at-risk mothers.

Entities:  

Year:  2019        PMID: 30893095      PMCID: PMC6650331          DOI: 10.1097/ANC.0000000000000601

Source DB:  PubMed          Journal:  Adv Neonatal Care        ISSN: 1536-0903            Impact factor:   1.968


  2 in total

Review 1.  An integrative review of maternal distress during neonatal intensive care hospitalization.

Authors:  Morgan A Staver; Tiffany A Moore; Kathleen M Hanna
Journal:  Arch Womens Ment Health       Date:  2020-08-27       Impact factor: 3.633

2.  Protocol for implementation of an evidence based parentally administered intervention for preterm infants.

Authors:  Debra Brandon; Karen Kavanaugh; Karen Gralton; Wei Pan; Evan R Myers; Bree Andrews; Michael Msall; Kathleen F Norr; Rosemary White-Traut
Journal:  BMC Pediatr       Date:  2021-03-24       Impact factor: 2.125

  2 in total

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