Literature DB >> 30892157

Treatments for Iron Deficiency (ID): Prospective Organic Iron Fortification.

Dan Wan1,2,3, Qinghua Wu4,5, Hengjia Ni2,6, Gang Liu1,2, Zheng Ruan1, Yulong Yin1,2.   

Abstract

Iron deficiency, one of the most common nutritional deficient disorders, frequently affects infants, adolescents and pregnant women and impairs growth, development and immune responses. Iron deficiency may also be secondary to gastrointestinal conditions such as gastrectomy and inflammatory bowel disease, as well as cancer and chronic uremia. Iron supplementation is the most commonly selected treatment option for iron deficiency. This review summarizes the iron compounds currently recommended for the iron fortification of foods and for clinical use. Additionally, this review discusses and compares the important aspects of high-quality iron compounds/products and classes of compounds that enhance iron bioavailability. The development of efficient iron fortification methods remains the most cost-effective and long-term approach to the treatment of iron deficiency or related anemia. To date, no orally administered options for iron fortification can sufficiently replace the parenteral administration of iron supplements, which includes the intramuscular injection of iron-dextran to neonatal piglets and intravenous injection of iron supplements to patients with gastrointestinal disorders. Iron bioavailability may be enhanced by encouraging customers to ingest iron-enriched foods together with dietary sources of vitamin C, folic acid and/or oligosaccharides. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  Iron deficiency; anemia; immune responses; iron fortification; iron supplements; organic iron.

Mesh:

Substances:

Year:  2019        PMID: 30892157     DOI: 10.2174/1381612825666190319111437

Source DB:  PubMed          Journal:  Curr Pharm Des        ISSN: 1381-6128            Impact factor:   3.116


  4 in total

1.  Dietary Supplementation of Ferrous Glycine Chelate Improves Growth Performance of Piglets by Enhancing Serum Immune Antioxidant Properties, Modulating Microbial Structure and Its Metabolic Function in the Early Stage.

Authors:  Jiayu Ma; Sujie Liu; Xiangshu Piao; Chunlin Wang; Jian Wang; Yu-Sheng Lin; Tzu-Ping Hsu; Li Liu
Journal:  Front Vet Sci       Date:  2022-04-25

Review 2.  Astrocytes in heavy metal neurotoxicity and neurodegeneration.

Authors:  Baoman Li; Maosheng Xia; Robert Zorec; Vladimir Parpura; Alexei Verkhratsky
Journal:  Brain Res       Date:  2021-01-05       Impact factor: 3.252

Review 3.  Regulation of Iron Homeostasis and Related Diseases.

Authors:  Yikun Li; Xiali Huang; Jingjing Wang; Ruiling Huang; Dan Wan
Journal:  Mediators Inflamm       Date:  2020-05-02       Impact factor: 4.711

Review 4.  Effects of iron deficiency and iron supplementation at the host-microbiota interface: Could a piglet model unravel complexities of the underlying mechanisms?

Authors:  Munawar Abbas; Zeynep Hayirli; Hal Drakesmith; Simon C Andrews; Marie C Lewis
Journal:  Front Nutr       Date:  2022-10-04
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.