Literature DB >> 3089198

Influenza virus strains with a fusion threshold of pH 5.5 or lower are inhibited by amantadine. Brief report.

W E Beyer, R W Ruigrok, H van Driel, N Masurel.   

Abstract

Nineteen influenza virus strains were examined for susceptibility to amantadine-HCl (AMT) and for pH-thresholds of haemagglutinin-induced haemolysis. Whereas pH-thresholds below 5.5 were not seen in AMT-resistant strains, AMT-sensitive strains showed pH-thresholds either below or above 5.5.

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Year:  1986        PMID： 3089198     DOI： 10.1007/bf01314156

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  17 in total

1.  Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

Authors:  S Ohkuma; B Poole
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

2.  Rapid acidification of endocytic vesicles containing alpha 2-macroglobulin.

Authors:  B Tycko; F R Maxfield
Journal:  Cell       Date:  1982-03       Impact factor: 41.582

3.  pH-dependent hemolysis by influenza, Semliki, Forest virus, and Sendai virus.

Authors:  J Lenard; D K Miller
Journal:  Virology       Date:  1981-04-30       Impact factor: 3.616

4.  Uncoating of influenza virus in endosomes.

Authors:  A Yoshimura; S Ohnishi
Journal:  J Virol       Date:  1984-08       Impact factor: 5.103

5.  [Genetic variability of the influenza virus during adaptation to a new host].

Authors:  A A Shilov; I A Rudneva; N P Obrosova-Serova; V M Zhdanov
Journal:  Dokl Akad Nauk SSSR       Date:  1984

6.  Susceptibility of influenza A viruses to amantadine is influenced by the gene coding for M protein.

Authors:  M D Lubeck; J L Schulman; P Palese
Journal:  J Virol       Date:  1978-12       Impact factor: 5.103

7.  Inhibition of virus-induced hemolysis with monoclonal antibodies to different antigenic areas on the hemagglutinin molecule of A/seal/Massachusetts/1/80 (H7N7) influenza virus.

Authors:  H Kida; R G Webster; R Yanagawa
Journal:  Arch Virol       Date:  1983       Impact factor: 2.574

8.  Infectious cell entry mechanism of influenza virus.

Authors:  A Yoshimura; K Kuroda; K Kawasaki; S Yamashina; T Maeda; S Ohnishi
Journal:  J Virol       Date:  1982-07       Impact factor: 5.103

9.  Studies on the adaptation of influenza viruses to MDCK cells.

Authors:  R Rott; M Orlich; H D Klenk; M L Wang; J J Skehel; D C Wiley
Journal:  EMBO J       Date:  1984-12-20       Impact factor: 11.598

10.  Membrane fusion mutants of Semliki Forest virus.

Authors:  M C Kielian; S Keränen; L Kääriäinen; A Helenius
Journal:  J Cell Biol       Date:  1984-01       Impact factor: 10.539
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  5 in total

Review 1.  Membrane fusion of enveloped viruses: especially a matter of proteins.

Authors:  D Hoekstra
Journal:  J Bioenerg Biomembr       Date:  1990-04       Impact factor: 2.945

2.  A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry.

Authors:  Anthony C Wong; Rohini G Sandesara; Nirupama Mulherkar; Sean P Whelan; Kartik Chandran
Journal:  J Virol       Date:  2010-01       Impact factor: 5.103

3.  H1N1 Swine Influenza Viruses Differ from Avian Precursors by a Higher pH Optimum of Membrane Fusion.

Authors:  Jan Baumann; Nancy Mounogou Kouassi; Emanuela Foni; Hans-Dieter Klenk; Mikhail Matrosovich
Journal:  J Virol       Date:  2015-11-25       Impact factor: 5.103

4.  Posttranslational oligomerization and cooperative acid activation of mixed influenza hemagglutinin trimers.

Authors:  F Boulay; R W Doms; R G Webster; A Helenius
Journal:  J Cell Biol       Date:  1988-03       Impact factor: 10.539

5.  Mutations in haemagglutinin that affect receptor binding and pH stability increase replication of a PR8 influenza virus with H5 HA in the upper respiratory tract of ferrets and may contribute to transmissibility.

Authors:  Holly Shelton; Kim L Roberts; Eleonora Molesti; Nigel Temperton; Wendy S Barclay
Journal:  J Gen Virol       Date:  2013-03-13       Impact factor: 3.891
  5 in total

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