Literature DB >> 30891597

Pulmonary vein-gap re-entrant atrial tachycardia following atrial fibrillation ablation: an electrophysiological insight with high-resolution mapping.

Seigo Yamashita1, Masateru Takigawa2, Arnaud Denis2, Nicolas Derval2, Yuichiro Sakamoto3, Masaharu Masuda4, Kohki Nakamura5, Yosuke Miwa6, Kenichi Tokutake1, Kenichi Yokoyama1, Michifumi Tokuda1, Seiichiro Matsuo1, Shigeto Naito5, Kyoko Soejima6, Michihiro Yoshimura1, Michel Haïssaguerre2, Pierre Jaïs2, Teiichi Yamane1.   

Abstract

AIMS: The circuit of pulmonary vein-gap re-entrant atrial tachycardia (PV-gap RAT) after atrial fibrillation ablation is sometimes difficult to identify by conventional mapping. We analysed the detailed circuit and electrophysiological features of PV-gap RATs using a novel high-resolution mapping system. METHODS AND
RESULTS: This multicentre study investigated 27 (7%) PV-gap RATs in 26 patients among 378 atrial tachycardias (ATs) mapped with Rhythmia™ system in 281 patients. The tachycardia cycle length (TCL) was 258 ± 52 ms with P-wave duration of 116 ± 28 ms. Three types of PV-gap RAT circuits were identified: (A) two gaps in one pulmonary vein (PV) (unilateral circuit) (n = 17); (B) two gaps in the ipsilateral superior and inferior PVs (unilateral circuit) (n = 6); and (C) two gaps in one PV with a large circuit around contralateral PVs (bilateral circuit) (n = 4). Rhythmia™ mapping demonstrated two distinctive entrance and exit gaps of 7.6 ± 2.5 and 7.9 ± 4.1 mm in width, respectively, the local signals of which showed slow conduction (0.14 ± 0.18 and 0.11 ± 0.10m/s) with fragmentation (duration 86 ± 27 and 78 ± 23 ms) and low-voltage (0.17 ± 0.13 and 0.17 ± 0.21 mV). Twenty-two ATs were terminated (mechanical bump in one) and five were changed by the first radiofrequency application at the entrance or exit gap. Moreover, the conduction time inside the PVs (entrance-to-exit) was 138 ± 60 ms (54 ± 22% of TCL); in all cases, this resulted in demonstrating P-wave with an isoelectric line in all leads.
CONCLUSION: This is the first report to demonstrate the detailed mechanisms of PV-gap re-entry that showed evident entrance and exit gaps using a high-resolution mapping system. The circuits were variable and Rhythmia™-guided ablation targeting the PV-gap can be curative. Published on behalf of the European Society of Cardiology. All rights reserved.
© The Author(s) 2019. For permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  Atrial fibrillation; Atrial tachycardia; Catheter ablation; High-resolution mapping; Pulmonary vein-gap re-entry; Rhythmia™

Year:  2019        PMID: 30891597     DOI: 10.1093/europace/euz034

Source DB:  PubMed          Journal:  Europace        ISSN: 1099-5129            Impact factor:   5.214


  2 in total

Review 1.  Challenges Associated with Interpreting Mechanisms of AF.

Authors:  Caroline H Roney; Andrew L Wit; Nicholas S Peters
Journal:  Arrhythm Electrophysiol Rev       Date:  2020-02-12

2.  How to map and ablate a pulmonary vein-to-right atrium breakthrough during simultaneous persistent pulmonary vein fibrillation and organized atrial fibrillation using an automated high-resolution mapping system.

Authors:  Takehito Sasaki; Kohki Nakamura; Kentaro Minami; Yutaka Take; Shigeto Naito
Journal:  HeartRhythm Case Rep       Date:  2020-10-24
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.