Michael C Topf1, Quang H Pham2, Jill N D'Souza3, Mark Chaskes1, Madalina Tuluc4, David M Cognetti1, Adam J Luginbuhl1. 1. 1 Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, Philadelphia, PA, USA. 2. 2 Department of Otolaryngology-Head and Neck Surgery, Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA. 3. 3 Department of Pediatric Otolaryngology-Head and Neck Surgery, Texas Children's Hospital, Houston, TX, USA. 4. 4 Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
Abstract
BACKGROUND: : Melanotic schwannoma is a rare tumor with indeterminate biologic behavior and varying treatment recommendations. METHODS: : We report 2 cases of pigmented melanotic schwannoma of the head and neck and perform literature review. The pathologic and immunohistochemical characteristics of melanotic schwannoma are reviewed. RESULTS: : Two cases of melanotic schwannoma are presented. Both cases underwent surgical resection with one patient receiving adjuvant radiation therapy. CONCLUSIONS: : Melanotic schwannoma is a rare nerve sheath tumor that is frequently mistaken for malignant melanoma. We describe 2 cases of pigmented melanotic schwannoma of the head and neck with different presentations and review the histopathological and immunohistochemical features.
BACKGROUND: : Melanotic schwannoma is a rare tumor with indeterminate biologic behavior and varying treatment recommendations. METHODS: : We report 2 cases of pigmented melanotic schwannoma of the head and neck and perform literature review. The pathologic and immunohistochemical characteristics of melanotic schwannoma are reviewed. RESULTS: : Two cases of melanotic schwannoma are presented. Both cases underwent surgical resection with one patient receiving adjuvant radiation therapy. CONCLUSIONS: : Melanotic schwannoma is a rare nerve sheath tumor that is frequently mistaken for malignant melanoma. We describe 2 cases of pigmented melanotic schwannoma of the head and neck with different presentations and review the histopathological and immunohistochemical features.
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