Literature DB >> 30882339

Effectiveness of two physical activity programs on non-alcoholic fatty liver disease. a randomized controlled clinical trial.

Isabella Franco1, Antonella Bianco, Maria Del Pilar Dìaz, Caterina Bonfiglio, Marisa Chiloiro, Sonia Alejandra Pou, Julia Becaria Coquet, Antonella Mirizzi, Alessandro Nitti, Angelo Campanella, Carla Maria Leone, Maria Gabriella Caruso, Mario Correale, Alberto Ruben Osella.   

Abstract

Introduction: To estimate the effectiveness of two physical activity programs on NAFLD.
Methods: Participants come from a survey conducted in southern Italy. Subjects with moderate or severe NAFLD were invited to participate. After giving informed consent, they completed a questionnaire, underwent ultrasonography and anthropometric measurements. Then they were randomized an Aerobic or a Combined Exercise program and followed up for six months. The first group followed a program of moderate aerobic activity lasting 30 minutes, 5 days per week. The second group did aerobic training with the addition of muscle training involving the large muscle groups, stimulating them to make more intense efforts, for a duration of 60 minutes, at least, 3 days a week. Compliance with the programs was measured. A mixed linear model was applied to the data.
Results: Compliance with Aerobic Exercise was homogeneous and increased over time. Combined Program compliance was equal to 100%. There was no significant difference in the NAFLD mean score by treatment at baseline and after six months. However, there was a significant reduction in the NAFLD mean score for treatments after six months. The NAFLD measured score was reduced by 22% in the Aerobic treatment group when confronted with the other program. In the Combined program, after 6 months, results showed to be less effective than the Aerobic Exercise in reducing the NAFLD score.
Conclusion: An aerobic exercise program is a realistic intervention which could be included as a part of primary prevention of several chronic diseases. Universidad Nacional de Córdoba

Entities:  

Keywords:  liver steatosis; aerobic exercise; resistance training; clinical trial

Mesh:

Year:  2019        PMID: 30882339     DOI: 10.31053/1853.0605.v76.n1.21638

Source DB:  PubMed          Journal:  Rev Fac Cien Med Univ Nac Cordoba        ISSN: 0014-6722


  5 in total

1.  Impact of exercise training on the sarcopenia criteria in non-alcoholic fatty liver disease: a systematic review and meta-analysis.

Authors:  Andrea Gonzalez; Mayalen Valero-Breton; Camila Huerta-Salgado; Oscar Achiardi; Felipe Simon; Claudio Cabello-Verrugio
Journal:  Eur J Transl Myol       Date:  2021-03-26

2.  Physical Activity and Low Glycemic Index Mediterranean Diet: Main and Modification Effects on NAFLD Score. Results from a Randomized Clinical Trial.

Authors:  Isabella Franco; Antonella Bianco; Antonella Mirizzi; Angelo Campanella; Caterina Bonfiglio; Paolo Sorino; Maria Notarnicola; Valeria Tutino; Raffaele Cozzolongo; Vito Giannuzzi; Laura R Aballay; Claudia Buongiorno; Irene Bruno; Alberto R Osella
Journal:  Nutrients       Date:  2020-12-28       Impact factor: 5.717

3.  The Effect of Low Glycemic Index Mediterranean Diet and Combined Exercise Program on Metabolic-Associated Fatty Liver Disease: A Joint Modeling Approach.

Authors:  Ritanna Curci; Antonella Bianco; Isabella Franco; Angelo Campanella; Antonella Mirizzi; Caterina Bonfiglio; Paolo Sorino; Fabio Fucilli; Giuseppe Di Giovanni; Nicola Giampaolo; Pasqua Letizia Pesole; Alberto Ruben Osella
Journal:  J Clin Med       Date:  2022-07-26       Impact factor: 4.964

4.  The Effect of Three Mediterranean Diets on Remnant Cholesterol and Non-Alcoholic Fatty Liver Disease: A Secondary Analysis.

Authors:  Angelo Campanella; Palma A Iacovazzi; Giovanni Misciagna; Caterina Bonfiglio; Antonella Mirizzi; Isabella Franco; Antonella Bianco; Paolo Sorino; Maria G Caruso; Anna M Cisternino; Claudia Buongiorno; Rosalba Liuzzi; Alberto R Osella
Journal:  Nutrients       Date:  2020-06-04       Impact factor: 5.717

5.  Exosomal FZD-7 Expression Is Modulated by Different Lifestyle Interventions in Patients with NAFLD.

Authors:  Maria Principia Scavo; Nicoletta Depalo; Federica Rizzi; Livianna Carrieri; Grazia Serino; Isabella Franco; Caterina Bonfiglio; Pasqua Letizia Pesole; Raffaele Cozzolongo; Vito Gianuzzi; Maria Lucia Curri; Alberto Ruben Osella; Gianluigi Giannelli
Journal:  Nutrients       Date:  2022-03-08       Impact factor: 5.717

  5 in total

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