Literature DB >> 3087758

Interferon: a cytotoxic T lymphocyte differentiation signal.

L K Chen, B Tourvieille, G F Burns, F H Bach, D Mathieu-Mahul, M Sasportes, A Bensussan.   

Abstract

Human T cell clones which were able to proliferate in response to specific stimuli but could not kill even in the presence of lectins were found to acquire the specific lytic function when interferon alpha or gamma was added on day 1 of the 7-day restimulation culture. These results demonstrate that interferon may act as a cytotoxic T lymphocyte differentiation signal. This signal can be blocked by the monoclonal antibody LeoA1 which recognizes a 70-kDa cell surface structure, involved in cytotoxic T lymphocyte differentiation.

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Year:  1986        PMID: 3087758     DOI: 10.1002/eji.1830160709

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN: 0014-2980            Impact factor:   5.532


  23 in total

Review 1.  Interferons 1992. How much of the promise has been realised?

Authors:  M A Volz; C H Kirkpatrick
Journal:  Drugs       Date:  1992-03       Impact factor: 9.546

2.  Phase I trial with recombinant interleukin-2 (rIL-2): immune activation by rIL-2 alone or following pretreatment with recombinant interferon-gamma.

Authors:  F Farace; C Mathiot; M Brandely; T Tursz; T Dorval; P Pouillart; F Triebel; T Hercend; W H Fridman
Journal:  Clin Exp Immunol       Date:  1990-11       Impact factor: 4.330

3.  Interferon-gamma (IFN-gamma) production in vivo in experimental autoimmune uveoretinitis.

Authors:  D G Charteris; S L Lightman
Journal:  Immunology       Date:  1992-03       Impact factor: 7.397

4.  Decrease in interferon-gamma production by peripheral blood mononuclear cells in patients with uterine cervical cancer.

Authors:  H Mori; T Hanabayashi; Y Yamada; T Tamaya
Journal:  J Clin Immunol       Date:  1990-01       Impact factor: 8.317

Review 5.  Surface proteins and glycoproteins of human leucocytes.

Authors:  V Horejsí; V Bazil
Journal:  Biochem J       Date:  1988-07-01       Impact factor: 3.857

6.  Immunological memory induced by genetically transduced tumor cells.

Authors:  M M Dar; Z Abdel-Wahab; C E Vervaert; T Darrow; J Barber; H F Seigler
Journal:  Ann Surg Oncol       Date:  1996-05       Impact factor: 5.344

7.  Detection of membrane-bound HLA-G translated products with a specific monoclonal antibody.

Authors:  A Bensussan; I G Mansur; V Mallet; A M Rodriguez; M Girr; E H Weiss; G Brem; L Boumsell; E Gluckman; J Dausset
Journal:  Proc Natl Acad Sci U S A       Date:  1995-10-24       Impact factor: 11.205

8.  Simian virus 40 large-T-antigen-specific rejection of mKSA tumor cells in BALB/c mice is critically dependent on both strictly tumor-associated, tumor-specific CD8(+) cytotoxic T lymphocytes and CD4(+) T helper cells.

Authors:  O Utermöhlen; C Schulze-Garg; G Warnecke; R Gugel; J Löhler; W Deppert
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

9.  Effects of a 24-week course of interferon-alpha therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma.

Authors:  Soo Cheol Jeong; Hiroshi Aikata; Yoshio Katamura; Takahiro Azakami; Tomokazu Kawaoka; Hiromi Saneto; Kiminori Uka; Nami Mori; Shintaro Takaki; Hideaki Kodama; Koji Waki; Michio Imamura; Hiroo Shirakawa; Yoshiiku Kawakami; Shoichi Takahashi; Kazuaki Chayama
Journal:  World J Gastroenterol       Date:  2007-10-28       Impact factor: 5.742

10.  Effects of cytokines on in vitro growth of tumor-infiltrating lymphocytes obtained from human primary and metastatic liver tumors.

Authors:  Y Shimizu; S Iwatsuki; R B Herberman; T L Whiteside
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

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