| Literature DB >> 30877425 |
Mary Ying-Fang Wang1, Paul Tuss2, Lihong Qi3.
Abstract
The inverse probability of treatment weighted (IPTW) estimator can be used to make causal inferences under two assumptions: (1) no unobserved confounders (ignorability) and (2) positive probability of treatment and of control at every level of the confounders (positivity), but is vulnerable to bias if by chance, the proportion of the sample assigned to treatment, or proportion of control, is zero at certain levels of the confounders. We propose to deal with this sampling zero problem, also known as practical violation of the positivity assumption, in a setting where the observed confounder is cluster identity, i.e., treatment assignment is ignorable within clusters. Specifically, based on a random coefficient model assumed for the potential outcome, we augment the IPTW estimating function with the estimated potential outcomes of treatment (or of control) for clusters that have no observation of treatment (or control). If the cluster-specific potential outcomes are estimated correctly, the augmented estimating function can be shown to converge in expectation to zero and therefore yield consistent causal estimates. The proposed method can be implemented in the existing software, and it performs well in simulated data as well as with real-world data from a teacher preparation evaluation study.Entities:
Keywords: common support; endogeneity; experimental treatment assignment assumption; hierarchical linear model; multilevel model; value added analysis
Mesh:
Year: 2019 PMID: 30877425 PMCID: PMC6507518 DOI: 10.1007/s11336-018-09657-y
Source DB: PubMed Journal: Psychometrika ISSN: 0033-3123 Impact factor: 2.500
Simulation results in evaluating IPTW and AIPTW in dealing with school-level confounders and practical positivity violations; , , and ; if and if where and c1–c4 were chosen to have , , , and 26% or 80% of the schools have practical positivity violations.
| PB% | T.SE | S.SE | 95% CP | |||||
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| 26% of the schools have practical positivity violations | ||||||||
| IPTW-orig | 0.034 | 1.718 | 2.778 | 1.722 | 2.888 | 0.948 | 0.909 | |
| IPTW-trim | 0.040 | 0.034 | 1.929 | 2.830 | 1.906 | 2.871 | 0.881 | 0.905 |
| AIPTW-SATC | 0.001 | 0.005 | 1.720 | 2.996 | 1.748 | 3.083 | 0.936 | 0.935 |
| AIPTW-RSATC | 0.001 | 1.707 | 2.753 | 1.734 | 2.854 | 0.941 | 0.938 | |
| 80% of the schools have practical positivity violations | ||||||||
| IPTW-orig | 0.095 | 1.839 | 3.052 | 1.891 | 3.147 | 0.879 | 0.741 | |
| IPTW-trim | 0.068 | 0.053 | 4.632 | 4.939 | 4.706 | 5.145 | 0.915 | 0.912 |
| AIPTW-SATC | 0.010 | 0.027 | 2.878 | 6.210 | 2.901 | 6.346 | 0.942 | 0.927 |
| AIPTW-RSATC | 0.001 | 0.003 | 2.356 | 4.535 | 2.392 | 4.559 | 0.929 | 0.935 |
Number of clusters is and average number of observations in each cluster is .
PB% = percentage bias calculated as the average difference between and divided by .
T.SE = the average estimated standard error of .
S.SE = the sample standard deviation of the 1000 .
95% CP = the percentage of confidence intervals covering the true .
Simulation results in evaluating IPTW and AIPTW in dealing with school-level confounders and practical positivity violation; , , , and ; if and if where and c1-c4 were chosen to have , 80% of the schools have practical positivity violations, and (0.4,0.4), (0.2,0.6), ().
| PB% | S.SE | Avg. Est. | S.SE | |||||||
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| IPTW-orig | 0.264 | 1.042 | 1.841 | 10.44 | 10.63 | 1.61 | 3.13 | 0.19 | ||
| IPTW-trim | 0.182 | 0.137 | 2.735 | 3.090 | 14.54 | 13.55 | 0.01 | 3.84 | 4.69 | 0.26 |
| AIPTW-SATC | 0.010 | 0.076 | 1.596 | 3.424 | 9.57 | 4.69 | 0.20 | 1.81 | 2.67 | 0.75 |
| AIPTW-RSATC | 0.030 | 1.333 | 2.619 | 9.30 | 4.82 | 0.27 | 1.80 | 2.59 | 0.72 | |
| IPTW-orig | 0.394 | 1.072 | 1.794 | 10.74 | 10.17 | 0.00 | 1.48 | 3.41 | 0.21 | |
| IPTW-trim | 0.106 | 0.208 | 2.877 | 3.044 | 15.15 | 13.00 | 0.03 | 3.63 | 4.84 | 0.28 |
| AIPTW-SATC | 0.010 | 0.124 | 1.662 | 3.304 | 9.55 | 4.73 | 0.25 | 1.58 | 2.65 | 0.71 |
| AIPTW-RSATC | 0.044 | 0.190 | 1.367 | 2.564 | 9.66 | 4.30 | 0.35 | 1.50 | 2.52 | 0.72 |
| IPTW-orig | 1.062 | 1.818 | 10.46 | 10.50 | 0.20 | 1.58 | 3.20 | 0.21 | ||
| IPTW-trim | 0.188 | 2.883 | 3.047 | 14.85 | 13.51 | 0.21 | 3.98 | 4.74 | 0.27 | |
| AIPTW-SATC | 0.004 | 1.644 | 3.460 | 9.52 | 4.77 | 0.46 | 2.07 | 2.42 | 0.66 | |
| AIPTW-RSATC | 1.301 | 2.534 | 8.94 | 5.20 | 0.79 | 2.17 | 2.21 | 0.45 | ||
Number of clusters is and average number of observations in each cluster is .
PB% = percentage bias calculated as the average difference between and divided by .
Avg. Est. = the average of the 1000 estimates of .
S.SE = the sample standard deviation of the 1000 estimates.
Simulation results in evaluating IPTW and AIPTW in dealing with school-level confounders and practical positivity violation; , , and ; if and if where and c1-c4 were chosen to have , 80% of the schools have practical positivity violations, and .
| PB% | S.SE | Avg. Est. | S.SE | |||||||
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| IPTW-orig | 1.083 | 1.842 | 10.49 | 10.82 | 0.02 | 1.63 | 3.15 | 0.19 | ||
| IPTW-trim | 0.167 | 2.854 | 3.114 | 14.86 | 13.77 | 3.99 | 4.76 | 0.25 | ||
| AIPTW-SATC | 0.004 | 1.656 | 3.543 | 9.60 | 4.76 | 1.87 | 2.56 | 0.73 | ||
| AIPTW-RSATC | 1.384 | 2.701 | 8.92 | 4.38 | 0.22 | 1.96 | 2.45 | 0.75 | ||
| IPTW-orig | 1.069 | 1.850 | 10.42 | 10.78 | 1.57 | 3.14 | 0.19 | |||
| IPTW-trim | 0.168 | 2.857 | 3.155 | 14.61 | 13.73 | 3.88 | 4.68 | 0.25 | ||
| AIPTW-SATC | 0.014 | 1.668 | 3.554 | 9.71 | 5.55 | 1.73 | 2.40 | 0.47 | ||
| AIPTW-RSATC | 1.450 | 2.882 | 9.02 | 4.50 | 1.52 | 2.49 | 0.71 | |||
| IPTW-orig | 1.043 | 1.751 | 9.91 | 10.22 | 0.03 | 1.63 | 3.43 | 0.21 | ||
| IPTW-trim | 0.262 | 2.629 | 3.022 | 13.75 | 13.19 | 4.00 | 5.05 | 0.28 | ||
| AIPTW-SATC | 0.018 | 1.564 | 3.297 | 9.88 | 5.16 | 1.80 | 2.62 | 0.57 | ||
| AIPTW-RSATC | 1.336 | 2.593 | 8.18 | 4.14 | 0.37 | 2.34 | 2.45 | 0.72 | ||
Number of clusters is and average number of observations in each cluster is .
PB% = percentage bias calculated as the average difference between and divided by .
Avg. Est. = the average of the 1000 estimates of .
S.SE = the sample standard deviation of the 1000 estimates.
Descriptive Statistics of the student-level CAT-6 score gains used in the real data analysis.
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| Mean | S.D. | Student-teaching | Intern-teaching | |||||
|---|---|---|---|---|---|---|---|---|---|
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| Mean | S.D. |
| Mean | S.D. | ||||
| Hispanic student population | |||||||||
| Language | 5547 | 15.93 | 39.73 | 4111 | 15.80 | 39.31 | 1436 | 16.28 | 40.93 |
| Reading | 5547 | 11.40 | 34.88 | 4111 | 10.92 | 34.36 | 1436 | 12.76 | 36.31 |
| Spelling | 5545 | 40.52 | 46.81 | 4109 |
| 45.71 | 1436 |
| 49.63 |
| Math | 5544 | 40.91 | 39.30 | 4105 | 41.26 | 39.18 | 1439 | 39.90 | 39.63 |
| Non-Hispanic student population | |||||||||
| Language | 1322 | 11.76 | 41.37 | 899 | 11.29 | 40.24 | 423 | 12.76 | 43.69 |
| Reading | 1322 | 8.30 | 37.39 | 899 | 8.60 | 36.03 | 423 | 7.66 | 40.15 |
| Spelling | 1316 | 33.87 | 46.03 | 895 | 33.52 | 46.45 | 421 | 34.61 | 45.17 |
| Math | 1317 | 41.34 | 45.65 | 895 | 41.79 | 45.40 | 422 | 40.36 | 46.22 |
number of test score gains.
significant difference between the two means at 0.05 level based on the two sample t test.
Schools whose student-level CAT-6 score gains were used in the real data analysis.
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| % without teachers prepared by | ||
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| Student-teaching | Intern-teaching | ||
| Hispanic student population | |||
| Language | 218 |
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| Reading | 218 |
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| Spelling | 217 |
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| Math | 217 |
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| Non-Hispanic student population | |||
| Language | 153 |
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| Reading | 153 |
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| Spelling | 154 |
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| Math | 154 |
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number of schools.
Evaluating two teacher preparation practices in effectiveness of teaching the grade 3 Hispanic students.
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| Est. | S.E. | p value | Est. | S.E. | p value | Est. | S.E. | p value | |
| IPTW-orig | |||||||||
| Language | 15.26 | 0.96 |
| 15.70 | 1.84 |
| 0.44 | 2.15 | 0.84 |
| Reading | 11.13 | 0.90 |
| 13.80 | 1.35 |
| 2.67 | 1.65 | 0.11 |
| Spelling | 39.85 | 1.14 |
| 45.86 | 2.40 |
| 6.01 | 2.64 | |
| Math | 40.57 | 1.19 |
| 38.98 | 1.65 |
| 1.99 | 0.42 | |
| IPTW-trim | |||||||||
| Language | 14.56 | 2.24 |
| 16.35 | 2.54 |
| 1.79 | 3.83 | 0.64 |
| Reading | 14.16 | 2.14 |
| 15.44 | 1.66 |
| 1.28 | 2.91 | 0.66 |
| Spelling | 42.48 | 2.14 |
| 47.95 | 3.18 |
| 5.47 | 3.79 | 0.15 |
| Math | 43.01 | 2.86 |
| 39.74 | 2.19 |
| 3.35 | 0.33 | |
| AIPTW-SATC | |||||||||
| Language | 14.56 | 1.25 |
| 18.20 | 3.10 |
| 3.64 | 3.52 | 0.30 |
| Reading | 11.90 | 1.25 |
| 17.39 | 2.49 |
| 5.49 | 3.01 | |
| Spelling | 40.86 | 1.41 |
| 51.09 | 4.65 |
| 10.23 | 4.86 | |
| Math | 40.63 | 1.58 |
| 39.53 | 3.34 |
| 3.38 | 0.75 | |
| AIPTW-RSATC | |||||||||
| Language | 14.61 | 1.17 |
| 18.45 | 2.48 |
| 3.85 | 3.22 | 0.23 |
| Reading | 10.97 | 1.04 |
| 13.90 | 2.02 |
| 2.93 | 2.59 | 0.26 |
| Spelling | 39.89 | 1.36 |
| 45.02 | 3.14 |
| 5.13 | 3.73 | 0.17 |
| Math | 40.52 | 1.31 |
| 39.23 | 2.40 |
| 3.04 | 0.67 | |
: the overall effectiveness of teachers prepared by student-teaching.
: the overall effectiveness of teachers prepared by intern-teaching.
: the relative effectiveness of teachers prepared by intern-teaching compared to teachers prepared
by student-teaching.
Evaluating two teacher preparation practices in effectiveness of teaching the grade 3 non-Hispanic students.
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| Est. | S.E. | Est. | S.E. | p value | Est. | S.E. | |||
| IPTW-orig | |||||||||
| Language | 11.96 | 1.48 |
| 12.83 | 2.74 |
| 0.86 | 3.14 | 0.78 |
| Reading | 8.34 | 1.62 |
| 6.69 | 3.58 | 0.06 | 3.78 | 0.66 | |
| Spelling | 33.17 | 1.75 |
| 36.29 | 2.55 |
| 3.13 | 3.06 | 0.31 |
| Math | 41.89 | 1.90 |
| 42.70 | 2.47 |
| 0.81 | 2.93 | 0.78 |
| IPTW-trim | |||||||||
| Language | 14.76 | 3.40 |
| 11.80 | 4.29 | 0.01 | 5.66 | 0.60 | |
| Reading | 4.66 | 4.27 | 0.28 | 4.09 | 6.64 | 0.54 | 6.51 | 0.93 | |
| Spelling | 30.89 | 3.45 |
| 39.31 | 3.52 |
| 8.42 | 4.64 | |
| Math | 42.91 | 4.35 |
| 45.88 | 2.82 |
| 2.97 | 4.40 | 0.50 |
| AIPTW-SATC | |||||||||
| Language | 12.10 | 2.24 |
| 11.53 | 7.41 | 0.12 | 7.90 | 0.94 | |
| Reading | 6.49 | 2.71 | 0.02 | 6.30 | 7.96 | 0.43 | 7.86 | 0.98 | |
| Spelling | 32.23 | 2.15 |
| 40.97 | 4.90 |
| 8.74 | 5.24 | |
| Math | 42.09 | 2.82 |
| 48.26 | 4.17 |
| 6.17 | 4.72 | 0.19 |
| AIPTW-RSATC | |||||||||
| Language | 12.18 | 2.13 |
| 11.88 | 4.78 | 0.01 | 6.23 | 0.96 | |
| Reading | 7.63 | 2.15 |
| 10.08 | 4.52 | 0.03 | 2.45 | 5.85 | 0.67 |
| Spelling | 31.84 | 1.97 |
| 39.75 | 3.60 |
| 7.91 | 4.60 | |
| Math | 40.74 | 2.34 |
| 43.72 | 3.70 |
| 2.98 | 4.98 | 0.55 |
: the overall effectiveness of teachers prepared by student-teaching.
: the overall effectiveness of teachers prepared by intern-teaching.
: the relative effectiveness of teachers prepared by intern-teaching compared to teachers prepared
by student-teaching.