Literature DB >> 30876683

New and Novel Therapies for Gynecologic Cancers.

Debra L Richardson1.   

Abstract

OBJECTIVE: To review recent therapies approved by the US Food and Drug Administration for the treatment of gynecologic malignancies. DATA SOURCES: PubMed, FDA.gov, ASCO.org.
CONCLUSION: The landscape for treating gynecologic malignancies is rapidly changing. Maintenance therapy now exists for women with advanced ovarian cancer after completing chemotherapy for both newly diagnosed and platinum-sensitive recurrent ovarian cancer. Anti-angiogenic therapy has many applications in gynecologic malignancies. Immunotherapy can be used in certain situations for women with gynecologic malignancies. IMPLICATIONS FOR NURSING PRACTICE: Biologic agents and immunotherapy have distinct side-effect profiles that nurses need to be aware of to optimize patient care and outcomes.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  bevacizumab; cervical cancer; endometrial cancer; ovarian cancer; parp inhibitors; pembrolizumab

Year:  2019        PMID: 30876683     DOI: 10.1016/j.soncn.2019.02.009

Source DB:  PubMed          Journal:  Semin Oncol Nurs        ISSN: 0749-2081            Impact factor:   2.315


  6 in total

1.  Paclitaxel, Carboplatin, and Bevacizumab in Advanced Cervical Cancer: A Treatment Response and Safety Analysis.

Authors:  Wanjun Tao; Jia Yang; Yongxian Jiang; Wenwen Chen; Yixin Wang
Journal:  Dose Response       Date:  2020-07-29       Impact factor: 2.658

Review 2.  Anti-angiogenic therapy in ovarian cancer: current situation & prospects.

Authors:  Yinping Liu; Yi Luo; Meiling Cai; Peijun Shen; Jun Li; Hailin Chen; Wei Bao; Yaping Zhu
Journal:  Indian J Med Res       Date:  2021-05       Impact factor: 5.274

Review 3.  Angiogenesis and vasculogenic mimicry as therapeutic targets in ovarian cancer.

Authors:  Dansaem Lim; Yeojin Do; Byung Su Kwon; Woochul Chang; Myeong-Sok Lee; Jongmin Kim; Jin Gu Cho
Journal:  BMB Rep       Date:  2020-06       Impact factor: 4.778

4.  Adipose-derived mesenchymal stem cells induced PAX8 promotes ovarian cancer cell growth by stabilizing TAZ protein.

Authors:  Yijing Chu; Chengzhan Zhu; Qianqian Wang; Meixin Liu; Wei Wan; Jun Zhou; Rendong Han; Jing Yang; Wenqiang Luo; Chong Liu; Huansheng Zhou; Min Li; Fengsheng Yu; Yuanhua Ye
Journal:  J Cell Mol Med       Date:  2021-04-08       Impact factor: 5.310

5.  Adipose-Derived Mesenchymal Stem Cells Enhance Ovarian Cancer Growth and Metastasis by Increasing Thymosin Beta 4X-Linked Expression.

Authors:  Yijing Chu; Min You; Jingjing Zhang; Guoqiang Gao; Rendong Han; Wenqiang Luo; Tingting Liu; Jianxin Zuo; Fuling Wang
Journal:  Stem Cells Int       Date:  2019-10-20       Impact factor: 5.443

6.  TGF-β signaling proteins and CYP24A1 may serve as surrogate markers for progesterone calcitriol treatment in ovarian and endometrial cancers of different histological types.

Authors:  Ana Paucarmayta; Hannah Taitz; Yovanni Casablanca; Gustavo C Rodriguez; G Larry Maxwell; Kathleen M Darcy; Viqar Syed
Journal:  Transl Cancer Res       Date:  2019-08       Impact factor: 1.241

  6 in total

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