Nicole Nugent1, Symielle A Gaston2, Jacqueline Perry3, Ariane L Rung4, Edward J Trapido4, Edward S Peters5. 1. Departments of Pediatrics and Psychiatry and Human Behavior, Brown University Warren Alpert School of Medicine, Providence, RI, United States. 2. Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States. 3. Division of Transplant Surgery, Brigham & Women's Hospital, Boston, MA, United States. 4. Epidemiology Program, Louisiana State University Health Sciences Center School of Public Health, New Orleans, LA, United States. 5. Epidemiology Program, Louisiana State University Health Sciences Center School of Public Health, New Orleans, LA, United States. Electronic address: epete1@lsuhsc.edu.
Abstract
BACKGROUND: Few prior studies have investigated the latent class structure of PTSD using DSM-5 symptoms. METHODS: To describe latent PTSD profiles among women who resided in Deepwater Horizon Oil Spill (DHOS)-affected coastal Louisiana communities, we used data from women enrolled in The Women and Their Children's Health (WaTCH) Study. Latent profile analysis was performed on the 20-item PTSD Checklist for DSM-5 (PCL-5) and model fit statistics for 2-class through 6-class solutions were compared. The pseudo-class draws method was employed on the best class solution to compare key covariates (including demographics, mental health indicators, DHOS exposure indicators, and trauma exposures) across classes. RESULTS: Among 1997 women (mean age 46.63 ± 12.14 years, 56.8% white, mean trauma categories 6.09 ± 2.98, 9.55% previously diagnosed with PTSD), model fit statistics supported a five-class solution: low symptoms (mean PCL-5 = 4.10), moderate without mood alterations (mean = 19.73), moderate with mood alterations (mean = 34.24), severe without risk-taking (mean = 55.75), and severe with risk-taking (mean = 53.80). Women in the low-symptom class were significantly more likely to be white, have finished high school, have an income of at least $40,001 per year, be married or living with a partner, and endorse fewer trauma categories than women in the four symptomatic classes. Women with moderate to severe symptoms often had co-morbid depressive symptoms and no prior PTSD diagnosis. LIMITATIONS: This study was limited by use of self-reported data and one-time assessment of PTSD symptoms. DISCUSSION: Five distinct latent profiles of DSM-5 PTSD symptoms consisted of notably different individuals. Most affected women did not report prior PTSD diagnosis. Future research and practice identifying and addressing barriers to care for trauma-affected women in these communities is warranted.
BACKGROUND: Few prior studies have investigated the latent class structure of PTSD using DSM-5 symptoms. METHODS: To describe latent PTSD profiles among women who resided in Deepwater Horizon Oil Spill (DHOS)-affected coastal Louisiana communities, we used data from women enrolled in The Women and Their Children's Health (WaTCH) Study. Latent profile analysis was performed on the 20-item PTSD Checklist for DSM-5 (PCL-5) and model fit statistics for 2-class through 6-class solutions were compared. The pseudo-class draws method was employed on the best class solution to compare key covariates (including demographics, mental health indicators, DHOS exposure indicators, and trauma exposures) across classes. RESULTS: Among 1997 women (mean age 46.63 ± 12.14 years, 56.8% white, mean trauma categories 6.09 ± 2.98, 9.55% previously diagnosed with PTSD), model fit statistics supported a five-class solution: low symptoms (mean PCL-5 = 4.10), moderate without mood alterations (mean = 19.73), moderate with mood alterations (mean = 34.24), severe without risk-taking (mean = 55.75), and severe with risk-taking (mean = 53.80). Women in the low-symptom class were significantly more likely to be white, have finished high school, have an income of at least $40,001 per year, be married or living with a partner, and endorse fewer trauma categories than women in the four symptomatic classes. Women with moderate to severe symptoms often had co-morbid depressive symptoms and no prior PTSD diagnosis. LIMITATIONS: This study was limited by use of self-reported data and one-time assessment of PTSD symptoms. DISCUSSION: Five distinct latent profiles of DSM-5 PTSD symptoms consisted of notably different individuals. Most affected women did not report prior PTSD diagnosis. Future research and practice identifying and addressing barriers to care for trauma-affected women in these communities is warranted.
Authors: Erika J Wolf; Mark W Miller; Annemarie F Reardon; Karen A Ryabchenko; Diane Castillo; Rachel Freund Journal: Arch Gen Psychiatry Date: 2012-07
Authors: Edward S Peters; Ariane L Rung; Megan H Bronson; Meghan M Brashear; Lauren C Peres; Symielle Gaston; Samaah M Sullivan; Kate Peak; David M Abramson; Elizabeth T H Fontham; Daniel Harrington; Evrim Oral; Edward J Trapido Journal: BMJ Open Date: 2017-07-10 Impact factor: 2.692
Authors: Jacqueline Michel; Edward H Owens; Scott Zengel; Andrew Graham; Zachary Nixon; Teresa Allard; William Holton; P Doug Reimer; Alain Lamarche; Mark White; Nicolle Rutherford; Carl Childs; Gary Mauseth; Greg Challenger; Elliott Taylor Journal: PLoS One Date: 2013-06-12 Impact factor: 3.240