Literature DB >> 3087281

In vitro activity of BRL 36650, a new penicillin.

H W Van Landuyt, A Lambert, J Boelaert, B Gordts.   

Abstract

Compared with four beta-lactam antibiotics and amikacin, BRL 36650 and BMY-28142 were the most active against 509 Enterobacteriaceae, including cefotaxime-resistant isolates and resistant laboratory mutants. BRL 36650 was more active than aztreonam, ceftazidime, and BMY-28142 against Acinetobacter spp., Pseudomonas aeruginosa, and other Pseudomonas spp.; all strains were inhibited by 2 micrograms/ml or less.

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Year:  1986        PMID： 3087281      PMCID： PMC176413          DOI： 10.1128/AAC.29.2.362

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

Review 1.  Emergence of resistance during therapy with the newer beta-lactam antibiotics: role of inducible beta-lactamases and implications for the future.

Authors:  C C Sanders; W E Sanders
Journal:  Rev Infect Dis       Date:  1983 Jul-Aug

2.  BRL 17421, a novel beta-lactam antibiotic, highly resistant to beta-lactamases, giving high and prolonged serum levels in humans.

Authors:  B Slocombe; M J Basker; P H Bentley; J P Clayton; M Cole; K R Comber; R A Dixon; R A Edmondson; D Jackson; D J Merrikin; R Sutherland
Journal:  Antimicrob Agents Chemother       Date:  1981-07       Impact factor: 5.191

3.  In vitro activity of BMY-28142 in comparison with those of other beta-lactam antimicrobial agents.

Authors:  A Tsuji; A Maniatis; M A Bertram; L S Young
Journal:  Antimicrob Agents Chemother       Date:  1985-04       Impact factor: 5.191

4.  In vitro antibacterial activity of BMY-28142, a new extended-spectrum cephalosporin.

Authors:  A Vuye; J Pijck
Journal:  Antimicrob Agents Chemother       Date:  1985-04       Impact factor: 5.191

5.  In vitro antibacterial properties of BRL 36650, a novel 6 alpha-substituted penicillin.

Authors:  M J Basker; R A Edmondson; S J Knott; R J Ponsford; B Slocombe; S J White
Journal:  Antimicrob Agents Chemother       Date:  1984-11       Impact factor: 5.191

6.  Chromosomal beta-lactamases of Enterobacter cloacae are responsible for resistance to third-generation cephalosporins.

Authors:  A H Seeberg; R M Tolxdorff-Neutzling; B Wiedemann
Journal:  Antimicrob Agents Chemother       Date:  1983-06       Impact factor: 5.191

7.  In vitro activity of temocillin (BRL 17421), a novel beta-lactam antibiotic.

Authors:  H W Van Landuyt; M Pyckavet; A Lambert; J Boelaert
Journal:  Antimicrob Agents Chemother       Date:  1982-10       Impact factor: 5.191
  7 in total
  2 in total

Review 1.  Cefepime clinical pharmacokinetics.

Authors:  M P Okamoto; R K Nakahiro; A Chin; A Bedikian
Journal:  Clin Pharmacokinet       Date:  1993-08       Impact factor: 6.447

Review 2.  Cefepime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  L B Barradell; H M Bryson
Journal:  Drugs       Date:  1994-03       Impact factor: 9.546
  2 in total

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