Literature DB >> 30870620

Original Antigenic Sin: Friend or Foe in Developing a Broadly Cross-Reactive Vaccine to Influenza?

Priyadharshini Devarajan1, Susan L Swain2.   

Abstract

In this issue of Cell Host & Microbe, two articles (Lee et al., 2019; Henry et al., 2019) find the influenza-specific antibody repertoire in humans becomes static over time and with age, despite repeated exposures. Identified persistent dominant clones target conserved viral epitopes, supporting the feasibility of a universal influenza vaccine.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID： 30870620      PMCID： PMC8822627          DOI： 10.1016/j.chom.2019.02.009

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN： 1931-3128            Impact factor:   21.023


  11 in total

Review 1.  Embracing microbial exposure in mouse research.

Authors:  Mathew A Huggins; Stephen C Jameson; Sara E Hamilton
Journal:  J Leukoc Biol       Date:  2018-09-27       Impact factor: 4.962

Review 2.  Original Antigenic Sin: How First Exposure Shapes Lifelong Anti-Influenza Virus Immune Responses.

Authors:  Ali Zhang; Hannah D Stacey; Caitlin E Mullarkey; Matthew S Miller
Journal:  J Immunol       Date:  2019-01-15       Impact factor: 5.422

3.  Persistent Antibody Clonotypes Dominate the Serum Response to Influenza over Multiple Years and Repeated Vaccinations.

Authors:  Jiwon Lee; Philipp Paparoditis; Andrew P Horton; Alexander Frühwirth; Jonathan R McDaniel; Jiwon Jung; Daniel R Boutz; Dania A Hussein; Yuri Tanno; Leontios Pappas; Gregory C Ippolito; Davide Corti; Antonio Lanzavecchia; George Georgiou
Journal:  Cell Host Microbe       Date:  2019-02-19       Impact factor: 21.023

4.  IL-6 Production by TLR-Activated APC Broadly Enhances Aged Cognate CD4 Helper and B Cell Antibody Responses In Vivo.

Authors:  Vinayak Brahmakshatriya; Yi Kuang; Priyadharshini Devarajan; Jingya Xia; Wenliang Zhang; Allen Minh Vong; Susan L Swain
Journal:  J Immunol       Date:  2017-03-01       Impact factor: 5.422

Review 5.  Understanding immunosenescence to improve responses to vaccines.

Authors:  Jörg J Goronzy; Cornelia M Weyand
Journal:  Nat Immunol       Date:  2013-04-18       Impact factor: 25.606

6.  Strategies to alleviate original antigenic sin responses to influenza viruses.

Authors:  Jin Hyang Kim; William G Davis; Suryaprakash Sambhara; Joshy Jacob
Journal:  Proc Natl Acad Sci U S A       Date:  2012-08-06       Impact factor: 11.205

Review 7.  Overcoming Barriers in the Path to a Universal Influenza Virus Vaccine.

Authors:  Lynda Coughlan; Peter Palese
Journal:  Cell Host Microbe       Date:  2018-07-11       Impact factor: 21.023

Review 8.  Aged-related shifts in T cell homeostasis lead to intrinsic T cell defects.

Authors:  Laura Haynes; Susan L Swain
Journal:  Semin Immunol       Date:  2012-05-06       Impact factor: 11.130

9.  Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals.

Authors:  Carole Henry; Nai-Ying Zheng; Min Huang; Alexandra Cabanov; Karla Thatcher Rojas; Kaval Kaur; Sarah F Andrews; Anna-Karin E Palm; Yao-Qing Chen; Yang Li; Katerina Hoskova; Henry A Utset; Marcos C Vieira; Jens Wrammert; Rafi Ahmed; Jeanne Holden-Wiltse; David J Topham; John J Treanor; Hildegund C Ertl; Kenneth E Schmader; Sarah Cobey; Florian Krammer; Scott E Hensley; Harry Greenberg; Xiao-Song He; Patrick C Wilson
Journal:  Cell Host Microbe       Date:  2019-02-19       Impact factor: 21.023

10.  Distinct patterns of B-cell activation and priming by natural influenza virus infection versus inactivated influenza vaccination.

Authors:  Xiao-Song He; Tyson H Holmes; Mrinmoy Sanyal; Randy A Albrecht; Adolfo García-Sastre; Cornelia L Dekker; Mark M Davis; Harry B Greenberg
Journal:  J Infect Dis       Date:  2014-10-21       Impact factor: 5.226
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  6 in total

Review 1.  How repertoire data are changing antibody science.

Authors:  Claire Marks; Charlotte M Deane
Journal:  J Biol Chem       Date:  2020-05-14       Impact factor: 5.157

2.  Understanding the Heterogeneous Population of Age-Associated B Cells and Their Contributions to Autoimmunity and Immune Response to Pathogens.

Authors:  Olivia Kugler-Umana; Priyadharshini Devarajan; Susan L Swain
Journal:  Crit Rev Immunol       Date:  2020       Impact factor: 2.214

3.  IgD+ age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged.

Authors:  Olivia Kugler-Umana; Wenliang Zhang; Yi Kuang; Jialing Liang; Catherine H Castonguay; Susan L Tonkonogy; Ann Marshak-Rothstein; Priyadharshini Devarajan; Susan L Swain
Journal:  Aging Cell       Date:  2022-09-02       Impact factor: 11.005

4.  Human Paramyxovirus Infections Induce T Cells That Cross-React with Zoonotic Henipaviruses.

Authors:  Rory D de Vries; Alwin de Jong; R Joyce Verburgh; Lucie Sauerhering; Gijsbert P van Nierop; Robert S van Binnendijk; Albert D M E Osterhaus; Andrea Maisner; Marion P G Koopmans; Rik L de Swart
Journal:  mBio       Date:  2020-07-07       Impact factor: 7.867

5.  "An Intrinsic Program Determines Key Age-Associated Changes in Adaptive Immunity that Limit Response to Non-Pathogens."

Authors:  Susan L Swain; Olivia Kugler-Umana; Susan Tonkonogy
Journal:  Front Aging       Date:  2021-06-24

6.  Application of volumetric absorptive microsampling (VAMS) to measure multidimensional anti-influenza IgG antibodies by the mPlex-Flu assay.

Authors:  Jiong Wang; Dongmei Li; Alexander Wiltse; Jason Emo; Shannon P Hilchey; Martin S Zand
Journal:  J Clin Transl Sci       Date:  2019-09-26
  6 in total

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