Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Successful Treatment of Antibiotic-resistant, Poly-microbial Bone Infection With Bacteriophages and Antibiotics Combination.

Literature DB >> 30869755

Successful Treatment of Antibiotic-resistant, Poly-microbial Bone Infection With Bacteriophages and Antibiotics Combination.

Ran Nir-Paz¹, Daniel Gelman^2,3, Ayman Khouri⁴, Brittany M Sisson⁵, Joseph Fackler⁵, Sivan Alkalay-Oren², Leron Khalifa², Amit Rimon^2,3, Ortal Yerushalmy², Reem Bader¹, Sharon Amit¹, Shunit Coppenhagen-Glazer², Matthew Henry⁶, Javier Quinones⁶, Francisco Malagon⁶, Biswajit Biswas⁶, Allon E Moses¹, Greg Merril⁵, Robert T Schooley⁷, Michael J Brownstein⁵, Yoram A Weil⁴, Ronen Hazan².

Abstract

A patient with a trauma-related left tibial infection associated with extensively drug-resistant Acinetobacter baumannii and multidrug-resistant Klebsiella pneumoniae was treated with bacteriophages and antibiotics. There was rapid tissue healing and positive culture eradication. As a result, the patient's leg did not have to be amputated and he is undergoing rehabilitation.

Entities: Disease Species

Keywords: antibiotic resistance; bacteriophage; orthopedic infections; phage; phage therapy

Year: 2019 PMID： 30869755 DOI： 10.1093/cid/ciz222

Source DB: PubMed Journal: Clin Infect Dis ISSN： 1058-4838 Impact factor: 9.079

Keyword Cloud
Cited

43 in total

1. Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research: Personalized Infectious Disease Medicine for the Most Vulnerable At-Risk Patients.

Authors: Austen L Terwilliger; Carmen Gu Liu; Sabrina I Green; Justin R Clark; Keiko C Salazar; Haroldo Hernandez Santos; Emmaline R Heckmann; Barbara W Trautner; Robert F Ramig; Anthony W Maresso
Journal: Phage (New Rochelle) Date: 2020-06-16

2. Bacteriophage delivering hydrogels reduce biofilm formation in vitro and infection in vivo.

Authors: James A Wroe; Christopher T Johnson; Andrés J García
Journal: J Biomed Mater Res A Date: 2019-09-05 Impact factor: 4.396

3. What's Old Is New Again: Bacteriophage Therapy in the 21st Century.

Authors: Saima Aslam; Robert T Schooley
Journal: Antimicrob Agents Chemother Date: 2019-12-20 Impact factor: 5.191

4. Isolation and genomic analysis of temperate phage 5W targeting multidrug-resistant Acinetobacter baumannii.

Authors: Wenyi Peng; Fei Zeng; Zhiying Wu; Zeyuan Jin; Wanxia Li; Mingzhuo Zhu; Qiuping Wang; Yigang Tong; Lili Chen; Qinqin Bai
Journal: Arch Microbiol Date: 2021-12-23 Impact factor: 2.552

Review 5. Therapeutics and delivery vehicles for local treatment of osteomyelitis.

Authors: Leah H Cobb; Emily M McCabe; Lauren B Priddy
Journal: J Orthop Res Date: 2020-04-21 Impact factor: 3.494

Review 6. Bacteriophage Therapy for Critical and High-Priority Antibiotic-Resistant Bacteria and Phage Cocktail-Antibiotic Formulation Perspective.

Authors: Gursneh Kaur; Ritika Agarwal; Rakesh Kumar Sharma
Journal: Food Environ Virol Date: 2021-06-12 Impact factor: 2.778

Successful Treatment of Antibiotic-resistant, Poly-microbial Bone Infection With Bacteriophages and Antibiotics Combination.

1. Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research: Personalized Infectious Disease Medicine for the Most Vulnerable At-Risk Patients.

2. Bacteriophage delivering hydrogels reduce biofilm formation in vitro and infection in vivo.

3. What's Old Is New Again: Bacteriophage Therapy in the 21st Century.

4. Isolation and genomic analysis of temperate phage 5W targeting multidrug-resistant Acinetobacter baumannii.

Review 5. Therapeutics and delivery vehicles for local treatment of osteomyelitis.

Review 6. Bacteriophage Therapy for Critical and High-Priority Antibiotic-Resistant Bacteria and Phage Cocktail-Antibiotic Formulation Perspective.

Review 7. Bacteriophage Capsid Modification by Genetic and Chemical Methods.

Review 8. Novel therapeutic interventions towards improved management of septic arthritis.

9. Isolation and Characterization of Streptococcus mutans Phage as a Possible Treatment Agent for Caries.

10. Low Immunogenicity of Intravesical Phage Therapy for Urogenitary Tract Infections.