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Literature DB >> 30869554

Precision prevention: A focused response to shifting paradigms in healthcare.

Kenneth S Ramos^1,2, Emma C Bowers², Marco A Tavera-Garcia², Irma N Ramos³.

Abstract

IMPACT STATEMENT: The study of LINE-1 retroelements and their role in the pathogenesis of diseases of the lung such as COPD and lung cancer may provide valuable diagnostic and therapeutic tools to identify pre-emptively individuals at risk of pulmonary disease progression. Limited information is presently available on the role of LINE-1 in the regulation of disease phenotypes and the development of novel therapeutics designed to curtail LINE-1-mediated pathogenesis. Successful implementation of precision prevention strategies may help to spare those impacted by obstructive pulmonary disease from continued deterioration, while realizing significant cost savings and improved quality of healthcare.

Entities: Disease

Keywords: COPD; LINE-1; Precision medicine; health promotion; healthcare; precision prevention

Mesh：

Year: 2019 PMID： 30869554 PMCID： PMC6425097 DOI： 10.1177/1535370219829759

Source DB: PubMed Journal: Exp Biol Med (Maywood) ISSN： 1535-3699

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