| Literature DB >> 3086907 |
G Bano, R K Raina, D B Sharma.
Abstract
The pharmacokinetics of carbamazepine was studied in 6 children with protein energy malnutrition (PEM) and in 6 healthy children. Plasma carbamazepine was estimated by enzyme multiplied immunoassay technique. Single-dose concentration profiles after 10 mg/kg of the drug showed lower plasma peak levels. The systemic availability (AUC 0-48 h) of the drug in PEM was also reduced. Based on these observations, suggestions have been made for rescheduling the dosage of the drug in PEM.Entities:
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Year: 1986 PMID： 3086907 DOI： 10.1159/000138174
Source DB: PubMed Journal: Pharmacology ISSN： 0031-7012 Impact factor: 2.547