Literature DB >> 3086832

High pressure liquid chromatographic determination of carbocisteine in human plasma and urine.

J Bron.   

Abstract

A method is described for the direct analysis of the amino acid carbocisteine in plasma and urine samples, following reaction with dabsyl chloride. Dabsylated carbocisteine is subjected to high pressure liquid chromatography with spectrophotometric detection at 425 nm. The usefulness of the method for bioavailability studies is discussed and compared with methods currently in use.

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Year:  1986        PMID： 3086832     DOI： 10.1007/bf02086147

Source DB:  PubMed          Journal:  Pharm Weekbl Sci        ISSN： 0167-6555


  8 in total

1.  Ligand exchange amino acid analysis: resolution of some amino sugars and cysteine derivatives.

Authors:  F W Wagner; S L Shepherd
Journal:  Anal Biochem       Date:  1971-06       Impact factor: 3.365

2.  Chromophoric labeling of amino acids with 4-dimethylaminoazobenzene-4'-sulfonyl chloride.

Authors:  J K Lin; J Y Chang
Journal:  Anal Chem       Date:  1975-08       Impact factor: 6.986

3.  Determination of urinary amino acids by liquid chromatography with "dabsyl chloride".

Authors:  J K Lin; C H Wang
Journal:  Clin Chem       Date:  1980-04       Impact factor: 8.327

4.  Comparative bioavailability of S-carboxymethylcysteine from two dosage forms: hard gelatin capsule and syrup.

Authors:  J M Aiache; J P Borel; J P Kantelip
Journal:  Biopharm Drug Dispos       Date:  1982 Jul-Sep       Impact factor: 1.627

5.  Excretion and biotransformation of carboxymethyl-cysteine in rat, dog, monkey and man.

Authors:  L B Turnbull; L Teng; J M Kinzie; J E Pitts; F M Pinchbeck; R B Bruce
Journal:  Xenobiotica       Date:  1978-10       Impact factor: 1.908

6.  Determination of carbocysteine from human plasma.

Authors:  W R Maynard; R B Bruce; G G Fox
Journal:  J Pharm Sci       Date:  1978-12       Impact factor: 3.534

7.  [The bioavailability and pharmacokinetics of two carbocysteine preparations after single and multiple dosing].

Authors:  D Lutz; W Gielsdorf; J Rasper; H Jaeger; M Albring; G Eisler; G Niebch
Journal:  Arzneimittelforschung       Date:  1985

8.  Identification of S-(carboxymethyl)-L-cysteine and thiodiglycolic acid, urinary metabolites of 2,2'-bis-(chloroethyl)-ether in the rat.

Authors:  G Müller; K Norpoth; R Eckard
Journal:  Cancer Lett       Date:  1979-09       Impact factor: 8.679
  8 in total
  2 in total

1.  Bioanalytical Method for Carbocisteine in Human Plasma by Using LC-MS/MS: A Pharmacokinetic Application.

Authors:  Shivanand Dhanure; Atulkumar Savalia; Pravinkumar More; Prashant Shirode; Kailas Kapse; Virag Shah
Journal:  Sci Pharm       Date:  2014-05-22

2.  Fluorimetric determination of some sulfur containing compounds through complex formation with terbium (Tb+3) and uranium (U+3).

Authors:  Elham Anwer Taha; Nagiba Yehya Hassan; Fahima Abdel Aal; Laila El-Sayed Abdel Fattah
Journal:  J Fluoresc       Date:  2007-04-18       Impact factor: 2.525
  2 in total

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