| Literature DB >> 30860533 |
Francesco V Reddavide1, Meiying Cui, Weilin Lin, Naiqiang Fu, Stephan Heiden, Helena Andrade, Michael Thompson, Yixin Zhang.
Abstract
We present a DNA-encoded chemical library, which allows dynamic selection followed by ligation of the encoding strands. As a chemical approach to mimic the genetic recombination process of adaptive immunity, the technology led to an enhanced enrichment factor and signal-to-noise ratio compared to static libraries.Mesh：
Substances：
Year: 2019 PMID： 30860533 DOI： 10.1039/c9cc01429b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222