Literature DB >> 30859648

Plexiform fibrohistiocytic tumor on the chest of a 5-year-old child and review of the literature.

Alexander Valiga1, Lane Neidig1, Carrie Ann Cusack1, Kevin Gaddis2,3, Melinda Jen2,3, Adam Rubin2,3, Amanda T Moon1,2,3.   

Abstract

Plexiform fibrohistiocytic tumor (PFT) is a rare neoplasm of mesenchymal origin that can be identified by its propensity for children and adolescents combined with a characteristic histologic arrangement of histiocytes and osteoclast-like giant cells whorled within tumor islands. A 5-year-old female presented with a raised, intermittently tender, and slowly enlarging tumor on her chest, which was histologically confirmed to be a PFT. We present this case along with a comprehensive review of PFT cases reported in the literature to describe the demographic, histologic, and rarely metastatic behavior of this entity. It is important to include PFT on the differential diagnosis of an enlarging tumor in the pediatric population.
© 2019 Wiley Periodicals, Inc.

Entities:  

Keywords:  dermatopathology; lumps/bumps; neoplasms-benign

Mesh:

Year:  2019        PMID: 30859648     DOI: 10.1111/pde.13805

Source DB:  PubMed          Journal:  Pediatr Dermatol        ISSN: 0736-8046            Impact factor:   1.588


  1 in total

1.  Plexiform fibrohistiocytic tumor: a clinicopathological and immunohistochemical study of 39 tumors, with evidence for a CSF1-producing "null cell" population.

Authors:  Judith Jebastin Thangaiah; Nooshin K Dashti; Abbas Agaimy; Karen Fritchie; Andrew L Folpe
Journal:  Virchows Arch       Date:  2022-09-07       Impact factor: 4.535

  1 in total

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