| Literature DB >> 30859648 |
Alexander Valiga1, Lane Neidig1, Carrie Ann Cusack1, Kevin Gaddis2,3, Melinda Jen2,3, Adam Rubin2,3, Amanda T Moon1,2,3.
Abstract
Plexiform fibrohistiocytic tumor (PFT) is a rare neoplasm of mesenchymal origin that can be identified by its propensity for children and adolescents combined with a characteristic histologic arrangement of histiocytes and osteoclast-like giant cells whorled within tumor islands. A 5-year-old female presented with a raised, intermittently tender, and slowly enlarging tumor on her chest, which was histologically confirmed to be a PFT. We present this case along with a comprehensive review of PFT cases reported in the literature to describe the demographic, histologic, and rarely metastatic behavior of this entity. It is important to include PFT on the differential diagnosis of an enlarging tumor in the pediatric population.Entities:
Keywords: dermatopathology; lumps/bumps; neoplasms-benign
Mesh:
Year: 2019 PMID: 30859648 DOI: 10.1111/pde.13805
Source DB: PubMed Journal: Pediatr Dermatol ISSN: 0736-8046 Impact factor: 1.588