Literature DB >> 30859233

[Delirium in geriatric urology patients].

K F Becher1.   

Abstract

BACKGROUND: Delirium is a common but often undiagnosed complication in geriatric patients following a major or minor operation. With 14-56% in patients over 70 years of age, it is one of the most frequent complications seen in hospitals. The link between the prescription of drugs with antimuscarinic effects and cognitive disturbance is also well known.
METHODS: Recognizing the presence of delirium and the criteria to establish the diagnosis of delirium will improve a clinician's ability to detect this complication. Treating delirium with non-pharmacologic, reduces the incidence and side effects of postoperative delirium. The purpose of this article is to describe the diagnosis and treatment of postoperative delirium.
RESULTS:sudden rise following fluctuating symptoms with decreased attentiveness, awareness and thinking are typical symptoms of delirium. The organic origin is not focused and must be considered. Transurethral resection (TUR) of the prostate and the bladder can increase the risk of bleeding, delirium and TUR syndrome. As simple instruments to assess signs and symptoms, the Clinical Assessment Method (CAM) and the Nurses Delirium Screening Scale (Nu-DESC) in the clinical setting are well examined.
CONCLUSIONS: Preoperatively screening and execution of a geriatric assessment to detect vulnerable elderly could be a first step in reduction of complication. Regularly screening for delirium reduces the pre-, post-, and perioperative complications in patients with delirium.

Entities:  

Keywords:  Antimuscarinic antagonists; Assessment; Cognitive dysfunction; Muscarinic receptors; Transurethral resection

Mesh:

Year:  2019        PMID: 30859233     DOI: 10.1007/s00120-019-0887-4

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  36 in total

1.  Effects of tolterodine, trospium chloride, and oxybutynin on the central nervous system.

Authors:  A Todorova; B Vonderheid-Guth; W Dimpfel
Journal:  J Clin Pharmacol       Date:  2001-06       Impact factor: 3.126

2.  Adverse cerebral effects of anaesthesia on old people.

Authors:  P D BEDFORD
Journal:  Lancet       Date:  1955-08-06       Impact factor: 79.321

3.  Comparative evaluation of central muscarinic receptor binding activity by oxybutynin, tolterodine and darifenacin used to treat overactive bladder.

Authors:  Tomomi Oki; Aiko Kageyama; Yukiko Takagi; Shinya Uchida; Shizuo Yamada
Journal:  J Urol       Date:  2007-02       Impact factor: 7.450

4.  Differential effects of the antimuscarinic agents darifenacin and oxybutynin ER on memory in older subjects.

Authors:  Gary Kay; Thomas Crook; Ludmyla Rekeda; Raul Lima; Ursula Ebinger; Miguel Arguinzoniz; Michael Steel
Journal:  Eur Urol       Date:  2006-04-19       Impact factor: 20.096

5.  Consequences of not recognizing delirium superimposed on dementia in hospitalized elderly individuals.

Authors:  D Fick; M Foreman
Journal:  J Gerontol Nurs       Date:  2000-01       Impact factor: 1.254

6.  Age-related changes in muscarinic cholinergic receptors in the living brain: a PET study using N-[11C]methyl-4-piperidyl benzilate combined with cerebral blood flow measurement in conscious monkeys.

Authors:  T Kakiuchi; H Ohba; S Nishiyama; K Sato; N Harada; S Nakanishi; H Tsukada
Journal:  Brain Res       Date:  2001-10-19       Impact factor: 3.252

7.  Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: longitudinal cohort study.

Authors:  Marie L Ancelin; Sylvaine Artero; Florence Portet; Anne-Marie Dupuy; Jacques Touchon; Karen Ritchie
Journal:  BMJ       Date:  2006-02-01

8.  Changes in adrenoreceptors in the prefrontal cortex of subjects with dementia: evidence of compensatory changes.

Authors:  P Szot; S S White; J L Greenup; J B Leverenz; E R Peskind; M A Raskind
Journal:  Neuroscience       Date:  2007-02-26       Impact factor: 3.590

9.  Functional selectivity of muscarinic receptor antagonists for inhibition of M3-mediated phosphoinositide responses in guinea pig urinary bladder and submandibular salivary gland.

Authors:  Carl P Nelson; Paul Gupta; Carolyn M Napier; Stefan R Nahorski; R A John Challiss
Journal:  J Pharmacol Exp Ther       Date:  2004-05-12       Impact factor: 4.030

Review 10.  [Delirium with dementia].

Authors:  T Kratz
Journal:  Z Gerontol Geriatr       Date:  2007-04       Impact factor: 1.281

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