Literature DB >> 30858326

Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling.

Sam Gandy1,2,3, Derek M Huffman4,5.   

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Year:  2019        PMID： 30858326      PMCID： PMC6442574          DOI： 10.1073/pnas.1901970116

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  20 in total

1.  Role of brain insulin receptor in control of body weight and reproduction.

Authors:  J C Brüning; D Gautam; D J Burks; J Gillette; M Schubert; P C Orban; R Klein; W Krone; D Müller-Wieland; C R Kahn
Journal:  Science       Date:  2000-09-22       Impact factor: 47.728

2.  Intracerebroventricular infusion of insulin-like growth factor-I ameliorates the age-related decline in hippocampal neurogenesis.

Authors:  R J Lichtenwalner; M E Forbes; S A Bennett; C D Lynch; W E Sonntag; D R Riddle
Journal:  Neuroscience       Date:  2001       Impact factor: 3.590

Review 3.  Insulin and IGF receptor signalling in neural-stem-cell homeostasis.

Authors:  Amber N Ziegler; Steven W Levison; Teresa L Wood
Journal:  Nat Rev Endocrinol       Date:  2014-12-02       Impact factor: 43.330

4.  Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting.

Authors:  E M Bailyes; B T Navé; M A Soos; S R Orr; A C Hayward; K Siddle
Journal:  Biochem J       Date:  1997-10-01       Impact factor: 3.857

Review 5.  The insulin paradox: aging, proteotoxicity and neurodegeneration.

Authors:  Ehud Cohen; Andrew Dillin
Journal:  Nat Rev Neurosci       Date:  2008-09-04       Impact factor: 34.870

Review 6.  Complex mechanisms linking neurocognitive dysfunction to insulin resistance and other metabolic dysfunction.

Authors:  Luke E Stoeckel; Zoe Arvanitakis; Sam Gandy; Dana Small; C Ronald Kahn; Alvaro Pascual-Leone; Aaron Pawlyk; Robert Sherwin; Philip Smith
Journal:  F1000Res       Date:  2016-03-15

7.  Type 2 Diabetes, Cognition, and Dementia in Older Adults: Toward a Precision Health Approach.

Authors:  Brenna Cholerton; Laura D Baker; Thomas J Montine; Suzanne Craft
Journal:  Diabetes Spectr       Date:  2016-11

8.  Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression.

Authors:  Weikang Cai; Masaji Sakaguchi; Andre Kleinridders; Gonzalo Gonzalez-Del Pino; Jonathan M Dreyfuss; Brian T O'Neill; Alfred K Ramirez; Hui Pan; Jonathon N Winnay; Jeremie Boucher; Michael J Eck; C Ronald Kahn
Journal:  Nat Commun       Date:  2017-03-27       Impact factor: 14.919

9.  Insulin-like growth factor-1 in CNS and cerebrovascular aging.

Authors:  William E Sonntag; Ferenc Deak; Nicole Ashpole; Peter Toth; Anna Csiszar; Willard Freeman; Zoltan Ungvari
Journal:  Front Aging Neurosci       Date:  2013-07-02       Impact factor: 5.750

10.  PTSD-Related Behavioral Traits in a Rat Model of Blast-Induced mTBI Are Reversed by the mGluR2/3 Receptor Antagonist BCI-838.

Authors:  Georgina Perez-Garcia; Rita De Gasperi; Miguel A Gama Sosa; Gissel M Perez; Alena Otero-Pagan; Anna Tschiffely; Richard M McCarron; Stephen T Ahlers; Gregory A Elder; Sam Gandy
Journal:  eNeuro       Date:  2018-01-30
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