Literature DB >> 30856487

The digit ratio (2D:4D) relationship with testosterone is moderated by physical training: Evidence of prenatal organizational influences on activational patterns of adult testosterone in physically-active women.

Blair T Crewther1, Christian J Cook2.   

Abstract

BACKGROUND: The 2nd to 4th digit ratio (2D:4D) is regarded as a sexually dimorphic trait governed by prenatal testosterone (T) and estradiol exposure. However, relationships between the 2D:4D and adult sex hormone concentrations are inconsistent in females. Environmental contingencies (e.g., physical training) may provide a stronger basis for establishing these linkages, particularly if the relationships are plastic and not fixed. AIMS: To investigate associations between 2D:4D, training hours and salivary T (sal-T) measures in physically-active women. STUDY
DESIGN: Descriptive and quasi-experimental monitoring across the follicular (day 7), ovulatory (day 14) and luteal (day 21) phases of three menstrual cycles.
SUBJECTS: 35 naturally-cycling women training regularly for sport (range 3-12 h a week). OUTCOME MEASURES: Morning sal-T concentrations and changes in sal-T to a physical and psychological stimulus (~10 min) were measured.
RESULTS: Both 2D:4D and training hours were related to morning sal-T concentrations in all three menstrual phases (p < 0.01) and their interaction was significant during ovulation. Follow-up testing revealed a negative 2D:4D and sal-T association in women reporting high, but not low, training hours each week. Participant 2D:4D was also related to sal-T changes under physical and/or psychological challenge across each menstrual phase (p < 0.01), whereas training hours and its interaction with 2D:4D were not significant predictors of these outcomes.
CONCLUSIONS: 2D:4D linkages with basal and challenge-induced sal-T changes were identified in women undertaking regular physical training. Training hours also moderated the 2D:4D link to morning sal-T, but with some menstrual-phase dependency. These complexities and environmental relationships may help reconcile conflicting results.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Androgens; Behaviour; Competition; Estrogen; Saliva; Stress

Mesh:

Substances:

Year:  2019        PMID: 30856487     DOI: 10.1016/j.earlhumdev.2019.02.008

Source DB:  PubMed          Journal:  Early Hum Dev        ISSN: 0378-3782            Impact factor:   2.079


  6 in total

1.  Gender Differences and Relationship of 2D:4D-Ratio, Mental Toughness and Dark Triad Traits among Active Young Adults.

Authors:  Seyed Hojjat Zamani Sani; Dena Sadeghi-Bahmani; Zahra Fathirezaie; Mohammad Taghi Aghdasi; Kosar Abbaspour; Georgian Badicu; Serge Brand
Journal:  Biology (Basel)       Date:  2022-06-05

2.  Digit Ratio (2D:4D) and Physical Performance in Female Olympic Athletes.

Authors:  Emma Eklund; Lena Ekström; John-Olof Thörngren; Magnus Ericsson; Bo Berglund; Angelica Lindén Hirschberg
Journal:  Front Endocrinol (Lausanne)       Date:  2020-05-12       Impact factor: 5.555

3.  No relationship between the digit ratios (2D:4D) and salivary testosterone change: Study on men under an acute exercise.

Authors:  Marta Kowal; Piotr Sorokowski; Agnieszka Żelaźniewicz; Judyta Nowak; Sylwester Orzechowski; Grzegorz Żurek; Alina Żurek; Anna Juszkiewicz; Lidia Wojtycka; Wiktoria Sieniuć; Małgorzata Poniatowska; Karolina Tarnowska; Kaja Kowalska; Katarzyna Drabik; Patrycja Łukaszek; Krzysztof Krawczyk; Tadeusz Stefaniak; Natalia Danek
Journal:  Sci Rep       Date:  2020-06-22       Impact factor: 4.379

4.  Digit ratio (2D:4D) in women and men with lung cancer.

Authors:  Anna Kasielska-Trojan; J T Manning; A Antczak; A Dutkowska; W Kuczyński; A Sitek; B Antoszewski
Journal:  Sci Rep       Date:  2020-07-09       Impact factor: 4.379

Review 5.  Variation among human populations in endometriosis and PCOS A test of the inverse comorbidity model.

Authors:  Bernard Crespi
Journal:  Evol Med Public Health       Date:  2021-09-17

6.  Handgrip strength and 2D : 4D in women: homogeneous samples challenge the (apparent) gender paradox.

Authors:  Nora Bäck; Katrin Schaefer; Sonja Windhager
Journal:  Proc Biol Sci       Date:  2021-12-08       Impact factor: 5.349

  6 in total

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