C Maia1, A Costa1,2, P Abreu2, M J Sa1,3. 1. Hospital de Sao Joao, 4200-351 Porto, Portugal. 2. Universidade do Porto, Porto, Portugal. 3. Universidade Fernando Pessoa. Facultade de Ciencias da Saude, Porto, Portugal.
Abstract
INTRODUCTION: There is poor knowledge on current hospitalizations in the multiple sclerosis (MS) population. The purpose of this study was to determine hospitalization causes and outcomes in a MS hospital-based cohort. PATIENTS AND METHODS: A retrospective chart review was performed on all patients admitted at our centre between August, 2009 and July, 2015, excluding those with no previous established diagnosis. RESULTS: 308 hospitalizations were included, representing a total of 155 patients (female, 67.5%). Median age at hospitalizations was 47 years, with median disease duration of 12 years. The most common overall reason for hospitalization was infectious diseases (22.1%), followed by MS relapses (12.7%) and neurogenic bladder (11%). The median length of hospitalization for all patients was 5 days and the progressive subtype of MS had longer lengths of hospitalization than the relapsing-remitting MS. Intensive care unit admission occurred in 23 cases (7.5%) and were associated with increased mortality and length of hospitalization. Of the 308 hospitalizations, 9 (2.9%) resulted in death. CONCLUSION: Infections are the most common cause of hospitalizations in our study, although MS relapses or complications related to MS continue to be significant causes of morbidity. Almost 8% of all MS hospitalizations required intensive care unit admission and these were related to longer admission lengths and higher death rates.
INTRODUCTION: There is poor knowledge on current hospitalizations in the multiple sclerosis (MS) population. The purpose of this study was to determine hospitalization causes and outcomes in a MS hospital-based cohort. PATIENTS AND METHODS: A retrospective chart review was performed on all patients admitted at our centre between August, 2009 and July, 2015, excluding those with no previous established diagnosis. RESULTS: 308 hospitalizations were included, representing a total of 155 patients (female, 67.5%). Median age at hospitalizations was 47 years, with median disease duration of 12 years. The most common overall reason for hospitalization was infectious diseases (22.1%), followed by MS relapses (12.7%) and neurogenic bladder (11%). The median length of hospitalization for all patients was 5 days and the progressive subtype of MS had longer lengths of hospitalization than the relapsing-remitting MS. Intensive care unit admission occurred in 23 cases (7.5%) and were associated with increased mortality and length of hospitalization. Of the 308 hospitalizations, 9 (2.9%) resulted in death. CONCLUSION: Infections are the most common cause of hospitalizations in our study, although MS relapses or complications related to MS continue to be significant causes of morbidity. Almost 8% of all MS hospitalizations required intensive care unit admission and these were related to longer admission lengths and higher death rates.
Authors: Ana Rodríguez-Regal; Laura Ramos-Rúa; Luis Anibarro-García; Ana María Lopez Real; María Del Campo Amigo-Jorrín Journal: Patient Prefer Adherence Date: 2021-01-29 Impact factor: 2.711
Authors: Irene Moreno-Torres; Virginia Meca Lallana; Lucienne Costa-Frossard; Celia Oreja-Guevara; Clara Aguirre; Elda María Alba Suárez; Mayra Gómez Moreno; Laura Borrega Canelo; Julia Sabín Muñoz; Yolanda Aladro; Alba Cárcamo; Elena Rodríguez García; Juan Pablo Cuello; Enric Monreal; Susana Sainz de la Maza; Fernando Pérez Parra; Francisco Valenzuela Rojas; Carlos López de Silanes de Miguel; Ignacio Casanova; Maria Luisa Martínez Gines; Rosario Blasco; Aida Orviz García; Luisa María Villar-Guimerans; Guillermo Fernández-Dono; Víctor Elvira; Carmen Santiuste; Mercedes Espiño; José Manuel García Domínguez Journal: Eur J Neurol Date: 2021-07-18 Impact factor: 6.288