C Samian1, S Ghaffar1, V Nandapalan1, S Santosh2. 1. Department of Otorhinolaryngology and Head and Neck Surgery, St Helens and Knowsley NHS Teaching Hospitals , Whiston, Merseyside , UK. 2. Department of Pathology, St Helens and Knowsley NHS Teaching Hospitals , Whiston, Merseyside , UK.
Abstract
INTRODUCTION: Malakoplakia is a rare chronic inflammatory disorder, predominantly affecting the urinary tract. In the head and neck region, it is very rare and may confuse the clinicians during investigations, as features may mimic malignancy. MATERIALS AND METHODS: We report a case of malakoplakia involving the parotid gland and review of the reported cases of malakoplakia in head and neck region. RESULTS: Histologically, this is the first classic case report of malakoplakia involving the parotid gland in the world literature. A total of 49 cases have been reported in the head and neck region; 38.7% of these are cutaneous. In soft tissue, the tongue is the most common site. Salivary gland involvement is very rare. Previously, submandibular salivary gland involvement has been reported. CONCLUSION: A possibility of malakoplakia should be considered as a differential diagnosis in patients with enlarged head and neck masses. Histology is essential to diagnose this benign inflammatory disorder and to differentiate from a malignant process.
INTRODUCTION:Malakoplakia is a rare chronic inflammatory disorder, predominantly affecting the urinary tract. In the head and neck region, it is very rare and may confuse the clinicians during investigations, as features may mimic malignancy. MATERIALS AND METHODS: We report a case of malakoplakia involving the parotid gland and review of the reported cases of malakoplakia in head and neck region. RESULTS: Histologically, this is the first classic case report of malakoplakia involving the parotid gland in the world literature. A total of 49 cases have been reported in the head and neck region; 38.7% of these are cutaneous. In soft tissue, the tongue is the most common site. Salivary gland involvement is very rare. Previously, submandibular salivary gland involvement has been reported. CONCLUSION: A possibility of malakoplakia should be considered as a differential diagnosis in patients with enlarged head and neck masses. Histology is essential to diagnose this benign inflammatory disorder and to differentiate from a malignant process.
Entities:
Keywords:
Head and neck; Histology; Malakoplakia; Parotid
Authors: Richard L Kradin; Thomas A Sheldon; Petur Nielsen; Martin Selig; Jennifer Hunt Journal: Ann Diagn Pathol Date: 2011-05-06 Impact factor: 2.090
Authors: Montey Garg; Karen A Eley; Stephen E Bond; Ketan A Shah; Lisa Browning; Stephen R Watt-Smith Journal: Head Neck Date: 2010-09 Impact factor: 3.147