Literature DB >> 30851121

Major Clinical Trials Failed the Amyloid Hypothesis of Alzheimer's Disease.

Yan-Mei Huang1, Jian Shen1, Hai-Lu Zhao1.   

Abstract

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Year:  2019        PMID： 30851121     DOI： 10.1111/jgs.15830

Source DB:  PubMed          Journal:  J Am Geriatr Soc        ISSN： 0002-8614            Impact factor:   5.562


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  13 in total

1.  HIV and FIV glycoproteins increase cellular tau pathology via cGMP-dependent kinase II activation.

Authors:  Matheus F Sathler; Michael J Doolittle; James A Cockrell; India R Nadalin; Franz Hofmann; Sue VandeWoude; Seonil Kim
Journal:  J Cell Sci       Date:  2022-06-21       Impact factor: 5.235

2.  Greater Diffusion Restriction in White Matter in Preclinical Alzheimer Disease.

Authors:  Andreana Benitez; Jens H Jensen; Kathryn Thorn; Siddhartha Dhiman; Stephanie Fountain-Zaragoza; William J Rieter; Maria Vittoria Spampinato; Eric D Hamlett; Paul J Nietert; Maria de Fatima Falangola; Joseph A Helpern
Journal:  Ann Neurol       Date:  2022-03-30       Impact factor: 11.274

3.  Co-activation of selective nicotinic acetylcholine receptors is required to reverse beta amyloid-induced Ca2+ hyperexcitation.

Authors:  Julianna L Sun; Sarah A Stokoe; Jessica P Roberts; Matheus F Sathler; Kaila A Nip; Jiayi Shou; Kaitlyn Ko; Susan Tsunoda; Seonil Kim
Journal:  Neurobiol Aging       Date:  2019-09-19       Impact factor: 4.673

Review 4.  Is γ-secretase a beneficial inactivating enzyme of the toxic APP C-terminal fragment C99?

Authors:  Frédéric Checler; Elissa Afram; Raphaëlle Pardossi-Piquard; Inger Lauritzen
Journal:  J Biol Chem       Date:  2021-03-01       Impact factor: 5.157

5.  Early diagnosis and treatment of Alzheimer's disease: new definitions and challenges.

Authors:  Marcos Pais; Luana Martinez; Octávio Ribeiro; Júlia Loureiro; Romel Fernandez; Leandro Valiengo; Paulo Canineu; Florindo Stella; Leda Talib; Marcia Radanovic; Orestes V Forlenza
Journal:  Braz J Psychiatry       Date:  2020-01-24       Impact factor: 2.697

Review 6.  Amyloids in Site-Specific Autoimmune Reactions and Inflammatory Responses.

Authors:  Yan-Mei Huang; Xue-Zhi Hong; Jian Shen; Li-Jun Geng; Yan-Hong Pan; Wei Ling; Hai-Lu Zhao
Journal:  Front Immunol       Date:  2020-01-09       Impact factor: 7.561

7.  Sodium-calcium exchanger isoform-3 targeted Withania somnifera (L.) Dunal therapeutic intervention ameliorates cognition in the 5xFAD mouse model of Alzheimer's disease.

Authors:  Henok Kessete Afewerky; Hao Li; Tongmei Zhang; Xinyan Li; Yacoubou Abdoul Razak Mahaman; Limin Duan; Pengwei Qin; Jiequn Zheng; Lei Pei; Youming Lu
Journal:  Sci Rep       Date:  2022-01-27       Impact factor: 4.379

8.  Ketogenic diet ameliorates cognitive impairment and neuroinflammation in a mouse model of Alzheimer's disease.

Authors:  Yunlong Xu; Chenyu Jiang; Junyan Wu; Peidong Liu; Xiaofei Deng; Yadong Zhang; Bo Peng; Yingjie Zhu
Journal:  CNS Neurosci Ther       Date:  2021-12-10       Impact factor: 5.243

9.  Amyloid β induces interneuron-specific changes in the hippocampus of APPNL-F mice.

Authors:  Katalin E Sos; Márton I Mayer; Virág T Takács; Abel Major; Zsuzsanna Bardóczi; Barnabas M Beres; Tamás Szeles; Takashi Saito; Takaomi C Saido; István Mody; Tamás F Freund; Gábor Nyiri
Journal:  PLoS One       Date:  2020-05-29       Impact factor: 3.240

Review 10.  Good problems to have? Policy and societal implications of a disease-modifying therapy for presymptomatic late-onset Alzheimer's disease.

Authors:  Misha Angrist; Anna Yang; Boris Kantor; Ornit Chiba-Falek
Journal:  Life Sci Soc Policy       Date:  2020-10-12
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