| Literature DB >> 3085094 |
F Malavasi, C Tetta, A Funaro, G Bellone, E Ferrero, A C Franzone, P Dellabona, R Rusci, L Matera, G Camussi.
Abstract
Triggering of large granular lymphocyte (LGL) Fc receptor with a specific monoclonal antibody (AB8.28) linked to an insoluble matrix induces cell activation, as witnessed by expression of HLA class II (DR and DQ) molecules and interleukin 2 receptor. Moreover, this event is accompanied by a concomitant release of platelet-activating factor by LGL. We conclude that the Fc receptor molecule identified by mAb AB8.28 represents a trigger for LGL activation.Mesh:
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Year: 1986 PMID: 3085094 PMCID: PMC323314 DOI: 10.1073/pnas.83.8.2443
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205