Literature DB >> 30850455

The Burden of Childhood Atopic Dermatitis in the Primary Care Setting: A Report from the Meta-LARC Consortium.

Jinan Al-Naqeeb1, Sankirtana Danner1, Lyle J Fagnan1, Katrina Ramsey1, LeAnn Michaels1, Julie Mitchell1, Kelsey Branca1, Cynthia Morris1, Donald E Nease1, Linda Zittleman1, Barcey Levy1, Jeanette Daly1, David Hahn1, Rowena J Dolor1, Hywel C Williams1, Joanne R Chalmers1, Jon Hanifin1, Susan Tofte1, Katharine E Zuckerman1, Karen Hansis1, Mollie Gundersen1, Julie Block1, Francie Karr1, Sandra Dunbrasky1, Kathy Siebe1, Kristen Dillon1, Ricardo Cibotti1, Jodi Lapidus1, Eric L Simpson2.   

Abstract

BACKGROUND: Little is known about the burden of atopic dermatitis (AD) encountered in US primary care practices and the frequency and type of skin care practices routinely used in children.
OBJECTIVE: To estimate the prevalence of AD in children 0 to 5 years attending primary care practices in the United States and to describe routine skin care practices used in this population.
DESIGN: A cross-sectional survey study of a convenience sample of children under the age of 5 attending primary care practices for any reason.
SETTING: Ten primary care practices in 5 US states.
RESULTS: Among 652 children attending primary care practices, the estimated prevalence of ever having AD was 24% (95% CI, 21-28) ranging from 15% among those under the age of 1 to 38% among those aged 4 to 5 years. The prevalence of comorbid asthma was higher among AD participants compared to those with no AD, namely, 12% and 4%, respectively (P < .001). Moisturizers with high water:oil ratios were most commonly used (ie, lotions) in the non-AD population, whereas moisturizers with low water:oil content (ie, ointments) were most common when AD was present.
CONCLUSIONS: Our study found a large burden of AD in the primary care practice setting in the US. The majority of households reported skin care practices that may be detrimental to the skin barrier, such as frequent bathing and the routine use of moisturizers with high water: oil ratios. Clinical trials are needed to identify which skin care practices are optimal for reducing the significant burden of AD in the community. © Copyright 2019 by the American Board of Family Medicine.

Entities:  

Keywords:  Atopic Dermatitis; Prevalence; Primary Health Care; Skin Care

Mesh:

Year:  2019        PMID: 30850455     DOI: 10.3122/jabfm.2019.02.180225

Source DB:  PubMed          Journal:  J Am Board Fam Med        ISSN: 1557-2625            Impact factor:   2.657


  3 in total

Review 1.  Recent Developments and Advances in Atopic Dermatitis: A Focus on Epidemiology, Pathophysiology, and Treatment in the Pediatric Setting.

Authors:  Lawrence F Eichenfield; Stephen Stripling; Selwyn Fung; Amy Cha; Andryann O'Brien; Lawrence A Schachner
Journal:  Paediatr Drugs       Date:  2022-06-13       Impact factor: 3.930

2.  A Community-based Assessment of Skin Care, Allergies, and Eczema (CASCADE): an atopic dermatitis primary prevention study using emollients-protocol for a randomized controlled trial.

Authors:  Brian Eichner; Le Ann C Michaels; Kelsey Branca; Katrina Ramsey; Julie Mitchell; Cynthia D Morris; Lyle J Fagnan; Rowena J Dolor; Nancy Elder; David L Hahn; Donald E Nease; Jodi Lapidus; Ricardo Cibotti; Julie Block; Eric L Simpson
Journal:  Trials       Date:  2020-03-04       Impact factor: 2.279

3.  A phase 2, open-label study of single-dose dupilumab in children aged 6 months to <6 years with severe uncontrolled atopic dermatitis: pharmacokinetics, safety and efficacy.

Authors:  A S Paller; E C Siegfried; E L Simpson; M J Cork; B Lockshin; M P Kosloski; M A Kamal; J D Davis; X Sun; G Pirozzi; N M H Graham; A Gadkari; L Eckert; M Ruddy; A Bansal
Journal:  J Eur Acad Dermatol Venereol       Date:  2020-11-08       Impact factor: 6.166

  3 in total

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