Mental distress in the rural Kazakhstani population exposed and non-exposed to radiation from the Semipalatinsk Nuclear Test Site.

The present study investigates the rates of depression, anxiety, somatic distress, and fatigue in a rural population of Abayskiy, Borodulikha and Mayskiy districts exposed to radiation from Semipalatinsk Nuclear Test Site in comparison with the unexposed population of Kurchum district. The sample size included 901 people, of whom 656 were residents of radioecological contaminated areas, while 245 resided at ecologically safe territories and had no radiation exposure in the past. Both study groups had no significant differences concerning age, sex, level of education, smoking habit, and alcohol consumption. The prevalence of depression, anxiety, somatic distress and fatigue in the exposed group was found to be considerably higher than that in the unexposed. Results of logistic regression analysis showed considerable differences in associations between depression and anxiety, as wells as between depression and somatic distress in the exposed group. Besides, depression was significantly associated with general fatigue, reduced activity, physical fatigue, reduced motivation and mental fatigue in the unexposed group. There is a need to tailor public health interventions focused on the identification and management of individuals exhibiting mental distress, including the provision of adequate information about radiation-induced health effects, quality routine check-ups and psychological counseling.