| Literature DB >> 30849141 |
Jian Yang1, Ran Cheng, Hualong Fu, Jing Yang, Mohanraja Kumar, Jie Lu, Yungen Xu, Steven H Liang, Mengchao Cui, Chongzhao Ran.
Abstract
In this report, we demonstrate that half-curcuminoid could be a better scaffold for PET tracer development. F-CRANAD-101 was designed and found to show significant response to both soluble and insoluble Aβs in the fluorescent spectral tests. PET imaging results indicated that 14 month and 5 month old APP/PS1 AD mice had higher signals in the brain than age-matched wild type mice.Entities:
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Year: 2019 PMID： 30849141 DOI： 10.1039/c8cc10166c
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222