Xueli Zhang1, Ting Hua1, Jingqi Zhu1, Kun Peng1, Jun Yang2, Sifeng Kang1, Tingting Xu1, Jian Hu1, Guangyu Tang3. 1. Department of Radiology, Shanghai TenthPeople's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072, China. 2. Department of Radiology, Tongren Hospital, Shanghai Jiaotong University School of Medical, Shanghai, 200336, China. 3. Department of Radiology, Shanghai TenthPeople's Hospital, Tongji University School of Medicine, 301 Middle Yanchang Road, Shanghai, 200072, China. tgy17@tongji.edu.cn.
Abstract
The study was to investigate the correlation between body compositions and bone mineral density (BMD) and to evaluate the body composition contribution to BMD. In male, LM showed positive effect on BMD. In female, SAT showed positive, and FM and F/L showed negative effect on BMD. PURPOSE: The purpose of the study was to investigate the correlation between body compositions and bone mineral density (BMD) performed by quantitative computed tomography (QCT), and to evaluate the body composition contribution to BMD. METHODS: Three hundred ninety-four participants, including 122 male (31%) and 272 female (69%), were divided into groups by gender, age, and BMD. BMD and body compositions [including fat mass (FM), lean mass (LM), bone mass/lean mass ratio (B/L), fat mass/lean mass ratio (F/L), total adipose tissue (TAT), subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT)] were retrospectively compared among groups using one-way ANOVA or t test. A stepwise multivariate analysis was used to evaluate the body composition contribution to BMD and produced models. RESULTS: In male, BMD got decreased with age (P < 0.05). LM increased before 30-49 years, then decreased (P < 0.05). TAT and SAT decreased with age (P < 0.05). LM in OP group was lower than those in the other two groups (P < 0.05). Through stepwise multivariate analysis, LM firstly got into model 1 (M1, β = 0.589). In female, BMD, LM TAT, and VAT were increased before 30-49 years, then decreased (P < 0.05). FM and F/L increased with age (P < 0.05). SAT decreased with age (P < 0.05). FM and F/L in OP group were higher than those in other groups. LM, B/L, TAT, and SAT in the OP group were lower than those in the other groups (P < 0.05). SAT entered the M1 with a maximum β value (β = 0.584). CONCLUSIONS: BMD and body compositions displayed different characteristics with age. In male, LM showed positive effect on BMD. In female, SAT showed positive, and FM and F/L showed negative effect on BMD.
The study was to investigate the correlation between body compositions and bone mineral density (BMD) and to evaluate the body composition contribution to BMD. In male, LM showed positive effect on BMD. In female, SAT showed positive, and FM and F/L showed negative effect on BMD. PURPOSE: The purpose of the study was to investigate the correlation between body compositions and bone mineral density (BMD) performed by quantitative computed tomography (QCT), and to evaluate the body composition contribution to BMD. METHODS: Three hundred ninety-four participants, including 122 male (31%) and 272 female (69%), were divided into groups by gender, age, and BMD. BMD and body compositions [including fat mass (FM), lean mass (LM), bone mass/lean mass ratio (B/L), fat mass/lean mass ratio (F/L), total adipose tissue (TAT), subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT)] were retrospectively compared among groups using one-way ANOVA or t test. A stepwise multivariate analysis was used to evaluate the body composition contribution to BMD and produced models. RESULTS: In male, BMD got decreased with age (P < 0.05). LM increased before 30-49 years, then decreased (P < 0.05). TAT and SAT decreased with age (P < 0.05). LM in OP group was lower than those in the other two groups (P < 0.05). Through stepwise multivariate analysis, LM firstly got into model 1 (M1, β = 0.589). In female, BMD, LM TAT, and VAT were increased before 30-49 years, then decreased (P < 0.05). FM and F/L increased with age (P < 0.05). SAT decreased with age (P < 0.05). FM and F/L in OP group were higher than those in other groups. LM, B/L, TAT, and SAT in the OP group were lower than those in the other groups (P < 0.05). SAT entered the M1 with a maximum β value (β = 0.584). CONCLUSIONS: BMD and body compositions displayed different characteristics with age. In male, LM showed positive effect on BMD. In female, SAT showed positive, and FM and F/L showed negative effect on BMD.
Entities:
Keywords:
Body compositions; Bone mineral density; Osteoporosis; QCT
Authors: Francesco Maria Achille Consoli; Yara Bernaldo de Quirós; Manuel Arbelo; Stefania Fulle; Marco Marchisio; Mario Encinoso; Antonio Fernandez; Miguel A Rivero Journal: Animals (Basel) Date: 2022-07-13 Impact factor: 3.231