| Literature DB >> 30846383 |
Curtis Wells Dewey1, Emma S Davies2, Huisheng Xie3, Joseph J Wakshlag4.
Abstract
Canine cognitive dysfunction (CCD) is the canine analog of human Alzheimer disease (AD). The pathophysiology of CCD/AD is multifaceted. CCD is common in aged (>8 years) dogs, affecting between 14% and 35% of the pet dog population. Apparent confusion, anxiety, disturbance of the sleep/wake cycle, and decreased interaction with owners are all common clinical signs of CCD. Although there is no cure for CCD, several proven effective therapeutic approaches are available for improving cognitive ability and maintaining a good quality of life; instituting such therapies early in the disease course is likely to have the greatest positive clinical effect.Entities:
Keywords: Alzheimer disease; Canine; Cognitive; Dementia; Dysfunction; Vascular; β-Amyloid
Mesh：
Year: 2019 PMID： 30846383 DOI： 10.1016/j.cvsm.2019.01.013
Source DB: PubMed Journal: Vet Clin North Am Small Anim Pract ISSN： 0195-5616 Impact factor: 2.093