Oral Cenk Aktas1, Wolfgang Metzger2, Ayman Haidar3, Yahya Açil4, Aydin Gülses4, Jörg Wiltfang4, Catharina Marques Sacramento5, Frank Philipp Nothdurft6. 1. Institute for Materials Science, Christian-Albrechts-University Kiel, Germany. 2. Department of Trauma, Hand and Reconstructive Surgery, Saarland University, Homburg, Saar, Germany. 3. Department of Prosthetic Dentistry and Dental Materials Sciences, Saarland University, Homburg, Saar, Germany. 4. Department of Oral and Maxillofacial Surgery, Christian-Albrecht-Universität zu Kiel, Kiel, Germany. 5. Department of Prosthesis and Periodontology, Division of Periodontics, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil. 6. Department of Prosthetic Dentistry and Dental Materials Sciences, Saarland University, Homburg, Saar, Germany. Electronic address: frank.nothdurft@uks.eu.
Abstract
BACKGROUND: Promoting the directional attachment of gingiva to the dental implant leads to the formation of tight connective tissue which acts as a seal against the penetration of oral bacteria. Such a directional growth is mostly governed by the surface texture. MATERIAL AND METHODS: In this study, three different methods, mechanical structuring, chemical etching and laser treatment, have been explored for their applicability in promoting cellular attachment and alignment of human primary gingival fibroblasts (HGFIBs). RESULTS: The effectiveness of mechanical structuring was shown as a simple and a cost-effective method to create patterns to align HGIFIBs. CONCLUSION: Combining mechanical structuring with chemical etching enhanced both cellular attachment and the cellular alignment.
BACKGROUND: Promoting the directional attachment of gingiva to the dental implant leads to the formation of tight connective tissue which acts as a seal against the penetration of oral bacteria. Such a directional growth is mostly governed by the surface texture. MATERIAL AND METHODS: In this study, three different methods, mechanical structuring, chemical etching and laser treatment, have been explored for their applicability in promoting cellular attachment and alignment of human primary gingival fibroblasts (HGFIBs). RESULTS: The effectiveness of mechanical structuring was shown as a simple and a cost-effective method to create patterns to align HGIFIBs. CONCLUSION: Combining mechanical structuring with chemical etching enhanced both cellular attachment and the cellular alignment.